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[Genotype, serotype and sensitivity to fluconazole of Candida albicans strains isolated from HIV-positive patients].

作者信息

Bastide J M, Pujol C, Mallié M, Reynes J

机构信息

Laboratoire d'Immunologie et Parasitologie, Faculté de Pharmacie, Montpellier.

出版信息

Bull Acad Natl Med. 1999;183(2):289-302; discussion 302-3.

Abstract

Genotype, serotype and susceptibility in vitro to fluconazole of 104 C. albicans strains isolated from HIV+ patients were studied. The possible correlations between genotype analysed by multilocus enzyme electrophoresis (MLEE) and phenotype of medical relevance (serotype and susceptibility to fluconazole) of Candida albicans isolated from these patients treated with fluconazole were evaluated by factorial correspondence analysis. No correlation was observed between genotype and in vitro or clinical response to fluconazole. In counterpart, serotype B C. albicans was associated with some multilocus genotypic patterns.

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