Hajdú P, Damm D
Arzneimittelforschung. 1976;26(12):2141-5.
A description is given of a new method for fluorometric determination of drugs in biological material. The assay is based on photochemical transformation of non-fluorescent compounds in fluorophors by short-wave UV light. The pharmacokinetics of the 2-[4-(4'-chlorophenoxy)-phenoxy]-propionic acid (HCG 004) serves as an example to demonstrate the usefulness of this method; reference is also made to analogously successful studies of other drugs.
本文描述了一种用于荧光测定生物材料中药物的新方法。该测定基于短波紫外光将非荧光化合物光化学转化为荧光团。以2-[4-(4'-氯苯氧基)-苯氧基]-丙酸（HCG 004）的药代动力学为例，证明了该方法的实用性；同时也提及了其他药物类似的成功研究。
