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蜂胶诱导人肝癌细胞系凋亡

Apoptosis induced by propolis in human hepatocellular carcinoma cell line.

作者信息

Choi Y H, Lee W Y, Nam S Y, Choi K C, Park Y E

机构信息

Department of Pathology, Chun-Chon Sacred Heart Hospital, Hallym University, Chun-Chon city, Kang Won-Do 200-060, Korea.

出版信息

Int J Mol Med. 1999 Jul;4(1):29-32. doi: 10.3892/ijmm.4.1.29.

DOI:10.3892/ijmm.4.1.29
PMID:10373633
Abstract

Propolis has been reported to exhibit a wide spectrum of activities including antibiotic, antiviral, anti-inflammatory, immunostimulatory and tumor carcinostatic properties. We showed propolis induced apoptosis in a human hepatoma cell line (SNU449) by FITC-Annexin V/PI staining. We also compared the apoptosis inducing effect between Korean and Commercial (Sigma # p-1010) propolis. There was no difference on apoptosis between them.

摘要

据报道,蜂胶具有广泛的活性,包括抗生素、抗病毒、抗炎、免疫刺激和肿瘤抑制特性。我们通过FITC-Annexin V/PI染色显示蜂胶可诱导人肝癌细胞系(SNU449)凋亡。我们还比较了韩国蜂胶和市售(Sigma # p-1010)蜂胶的凋亡诱导效果。它们之间在凋亡方面没有差异。

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J Indian Soc Periodontol. 2016 Sep-Oct;20(5):543-548. doi: 10.4103/0972-124X.201696.
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Propolis mouthwash: A new beginning.蜂胶漱口水:新的开端。
J Indian Soc Periodontol. 2011 Apr;15(2):121-5. doi: 10.4103/0972-124X.84379.
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Study of apoptosis in human liver cancers.人类肝癌细胞凋亡的研究。
World J Gastroenterol. 2002 Apr;8(2):247-52. doi: 10.3748/wjg.v8.i2.247.