Körber W, Laier-Groeneved G, Criée C P
Abteilung für Beatmungsmedizin, Schlaflabor und Pneumologie der Medizinischen Klinik des Evangelischen Krankenhauses Weende, Bovenden-Lenglern.
Med Klin (Munich). 1999 Apr;94(1 Spec No):45-50.
In this present retrospective study we examined 62 long-term ventilated patients, whose weaning from respirator failed, for endoscopic airway complications and the frequency of consecutive surgery required. Furthermore noninvasive volume-controlled intermittent ventilation was evaluated as an alternative method to tracheostomy for maintaining mechanical ventilation and weaning of patients with chest wall disorders, neuromuscular and chronic obstructive lung disease.
25 patients with endotracheal tube and 37 with tracheostomy who had been long-term ventilated in different intensive care units for 18 +/- 12 respectively 57 +/- 27 days (19 +/- 12 days via endotracheal tube) could be weaned successfully consequently using a volume-controlled intermittent ventilation via an individually adapted face mask. We found 2 patients of the group with endotracheal intubation (median age 59 +/- 15 years, 11 female, 14 male, median duration of mechanical ventilation via tube 18 +/- 12 days) to have visible injuries of the respiratory tract without consecutive surgery being necessary. All of them were successfully weaned from respirator via noninvasive ventilation (in 2 of them completely spontaneous breathing was re-established, 23 patients needed intermittent ventilation at home). Of the 37 patients with tracheostomy (median age 59 +/- 15 years, 15 female, 22 male, median duration of mechanical ventilation 57 +/- 27 days, tracheostomy on day 19 +/- 12) 19 cases (51%) showed endoscopically visible injuries of the respiratory tract of whom 7 cases (19%) were severe and made consecutive surgery necessary. 29 patients were discharged with noninvasive ventilation at home, 5 needed further invasive ventilation via tracheostomy and 3 patients breathed spontaneously without ventilatory support. The incidence of severe tracheal stenosis following long-term ventilation via tracheostomy was nearly 20% (1 tracheoesophageal fistula) and needed surgical treatment.
As even duration of ventilation via tracheal tube and mode of ventilation before transfer to our clinic was comparable in both groups noninvasive ventilation is an appropriate alternative to tracheostomy following endotracheal intubation for maintaining ventilatory support, especially for patients with chronic ventilatory insufficiency.
在这项回顾性研究中,我们检查了62例长期机械通气但撤机失败的患者,观察其气道内镜并发症及后续所需连续手术的频率。此外,还评估了无创容量控制间歇通气作为一种替代气管切开术的方法,用于维持胸壁疾病、神经肌肉疾病和慢性阻塞性肺疾病患者的机械通气及撤机。
25例气管插管患者和37例气管切开患者分别在不同重症监护病房长期机械通气18±12天和57±27天(气管插管通气19±12天),随后通过个体化适配的面罩采用容量控制间歇通气成功撤机。我们发现气管插管组中有2例患者(中位年龄59±15岁,女性11例,男性14例,经气管插管机械通气中位时长18±12天)存在呼吸道可见损伤,但无需后续手术。所有这些患者均通过无创通气成功撤机(其中2例完全恢复自主呼吸,23例患者在家中需要间歇通气)。在37例气管切开患者中(中位年龄59±15岁,女性15例,男性22例,机械通气中位时长57±27天;气管切开于第19±12天进行),19例(51%)在内镜下可见呼吸道损伤,其中7例(19%)损伤严重,需要进行后续手术。29例患者在家中依靠无创通气出院,5例需要通过气管切开进行进一步有创通气,3例患者无需通气支持可自主呼吸。长期气管切开通气后严重气管狭窄的发生率近20%(1例气管食管瘘),需要手术治疗。
由于两组患者气管插管通气时长及转至我院前的通气模式相当,无创通气是气管插管后替代气管切开维持通气支持的合适选择,尤其适用于慢性通气功能不全患者。