Wu Y C, Tung C C, Deng J S, Lü Y C
Zhonghua Min Guo Wei Sheng Wu Xue Za Zhi. 1976 Dec;9(3-4):45-8.
Prevalence of cytoplasmic antibodies--smooth muscle antibodies (SMA), gastric parietal cell antibodies (GPA), and mitochondrial antibodies (MTA)--was evaluated in 148 normal persons and 168 patients by indirect immunofluorescent method. Their prevalence in normal persons was 0%, 2% and 0% for SMA, GPA and MTA respectively, while SMA and MTA were positive in 5.7% and 8.6% of the 35 systemic lupus erythematosus (SLE) patients respectively. The difference in the prevalence of SMA and MTA between these two groups was statistically significant. The higher prevalence of these antibodies and the occurrence of various kinds of antibodies in SLE patients support the thesis that SLE is an autoimmune phenomenon.
采用间接免疫荧光法评估了148名正常人和168名患者体内细胞质抗体——平滑肌抗体（SMA）、胃壁细胞抗体（GPA）和线粒体抗体（MTA）的流行情况。在正常人中，SMA、GPA和MTA的流行率分别为0%、2%和0%，而在35例系统性红斑狼疮（SLE）患者中，SMA和MTA的阳性率分别为5.7%和8.6%。两组之间SMA和MTA流行率的差异具有统计学意义。这些抗体在SLE患者中的较高流行率以及各种抗体的出现支持了SLE是一种自身免疫现象这一论点。
