Reynolds L, Struik S, Nadel S
Department of Paediatrics Paediatric Infectious Diseases Unit St Mary's Hospital Medical School London W2 1NY, UK.
Arch Dis Child Fetal Neonatal Ed. 1999 Jul;81(1):F69-70. doi: 10.1136/fn.81.1.f69.
Two infants with severe varicella are reported. They received varicella zoster immunoglobulin (VZIG) without concurrent information to parents or carers regarding further care. In both these cases there was a three day delay between the onset of symptoms and initiation of aciclovir. This delay was due to lack of awareness of the high risk of varicella in these infants. Infants born to mothers with onset of chickenpox 4 days before to 2 days after delivery are at risk of fatal varicella, despite the use of VZIG prophylaxis.
报告了两名患有重症水痘的婴儿。他们接受了水痘带状疱疹免疫球蛋白（VZIG），但未同时向父母或护理人员提供有关进一步护理的信息。在这两例病例中，症状出现与开始使用阿昔洛韦之间均有三天的延迟。这种延迟是由于对这些婴儿中水痘高风险缺乏认识所致。尽管使用了VZIG预防措施，但在分娩前4天至分娩后2天内母亲出现水痘的婴儿仍有患致命性水痘的风险。
