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轴突导向:以Slit蛋白开启与终止

Axon guidance: starting and stopping with slit.

作者信息

Guthrie S

机构信息

Department of Developmental Neurobiology, Hodgkin Building King's College, Guy's Campus, London, SE1 9RT, UK.

出版信息

Curr Biol. 1999 Jun 17;9(12):R432-5. doi: 10.1016/s0960-9822(99)80274-7.

Abstract

As developing axons navigate, they exhibit various behaviours: extending and branching, pausing, changing direction, retracting. Now, the Slit protein has been discovered to have striking positive and negative effects on axon growth and guidance.

摘要

在发育中的轴突进行导航时,它们会表现出各种行为:延伸、分支、暂停、改变方向、回缩。现在,已发现Slit蛋白对轴突生长和导向具有显著的正向和负向作用。

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