Pirrung M C
Department of Chemistry, Levine Science Research Center, Box 90317, Duke University, Durham, NC 27708-0317, USA.
Chem Biol. 1999 Jun;6(6):R167-75. doi: 10.1016/S1074-5521(99)80044-1.
The phosphorylation of histidine is the first step in many signal transduction cascades in bacteria, yeast and higher plants. The transfer of a very reactive phosphoryl group from phosphorylated histidine kinase to an acceptor is an essential step in many cellular signaling responses.
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