Mujica V R, Conklin J
Division of Gastroenterology/Hepatology, University of Iowa College of Medicine, Iowa City 52242, USA.
Postgrad Med. 1999 Jun;105(7):131-4, 141-2, 145. doi: 10.3810/pgm.1999.06.620.
Swallowing disorders can be divided into oropharyngeal dysphagia and esophageal dysphagia. The most common cause of oropharyngeal dysphagia is cerebrovascular accidents; other causes may include oropharyngeal structural lesions, systematic and local muscular diseases, and diverse neurologic disorders. Esophageal dysphagia may result from neuromuscular disorders, mortality abnormalities, and intrinsic or extrinsic obstructive lesions. Through clinical history taking helps define the tpe of dysphagia and can guide diagnostic testing. Important questions to ask patients with the disorder include specific features of the dysphagia, its onset and progression, accompanying problems, and eating habits adopted to relieve symptoms. Videofluoroscopy should be the initial test in evaluating oropharyngeal dysphagia. Barium-contrast esophagography identifies most anatomic causes of dysphagia and some motor disorders and is better tha endoscopy at identifying extrinsic esophageal compression and intramural lesions not involving the esophageal mucosa. Cine-esophagography may provide clues to a possible esophageal motor disorder causing dysphagia. Endoscopy is the test of choice if obstruction or gastroesophageal reflux disease is suspected, because biopsies can confirm the presence of esophagitis and provide specific pathologic identification of the obstructive lesion. In addition, therapeutic dilatation of a stricture and removal of foreign bodies can be accomplished as part of the evaluation procedure. When no obvious source of dysphagia is apparent after radiologic and endoscopic assessment, manometry for possible motility disorder should be considered.
吞咽障碍可分为口咽性吞咽困难和食管性吞咽困难。口咽性吞咽困难最常见的病因是脑血管意外;其他病因可能包括口咽部结构病变、系统性和局部肌肉疾病以及各种神经障碍。食管性吞咽困难可能由神经肌肉疾病、动力异常以及内在或外在阻塞性病变引起。通过临床病史采集有助于明确吞咽困难的类型,并可指导诊断性检查。向患有该疾病的患者询问的重要问题包括吞咽困难的具体特征、其发作和进展情况、伴随问题以及为缓解症状而采取的饮食习惯。电视荧光吞咽造影检查应作为评估口咽性吞咽困难的初始检查。钡剂食管造影可识别大多数吞咽困难的解剖学病因和一些动力障碍,在识别外在食管压迫和不涉及食管黏膜的壁内病变方面比内镜检查更好。动态食管造影可能为导致吞咽困难的潜在食管动力障碍提供线索。如果怀疑有梗阻或胃食管反流病,内镜检查是首选检查,因为活检可证实食管炎的存在,并对阻塞性病变进行特异性病理鉴定。此外,作为评估程序的一部分,可进行狭窄的治疗性扩张和异物取出。当经放射学和内镜评估后仍未发现明显的吞咽困难病因时,应考虑进行测压以排查可能的动力障碍。