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常见胃肠道症状:吞咽困难。

Common gastrointestinal symptoms: dysphagia.

作者信息

Fashner Julia, Gitu Alfred Chege

机构信息

Lee Memorial Hospital, 2780 Cleveland Avenue Suite 709, Fort Myers, FL 33901,

出版信息

FP Essent. 2013 Oct;413:11-5.

Abstract

Swallowing occurs in 3 phases: oral, pharyngeal, and esophageal. Oropharyngeal dysphagia typically is a result of neuromuscular disorders, such as stroke and parkinsonism, or of mucosal dryness caused by drugs or radiation therapy. Esophageal dysphagia is commonly caused by anatomic defects of the esophagus, such as reflux disease; motility disorders, such as achalasia; or eosinophilic esophagitis. If oropharyngeal dysphagia is suspected, the patient should undergo initial testing with a water or semisolid bolus swallow test. If results are positive, the diagnosis can be confirmed with a videofluoroscopic swallowing study. If esophageal dysphagia is suspected, patients typically undergo endoscopic esophagogastroduodenoscopy. Management of confirmed oropharyngeal dysphagia involves short-term compensation strategies, such as postural changes or food thickening, to minimize the risk of aspiration. This is followed by rehabilitation that may involve swallowing exercises with biofeedback or electrical stimulation of the swallowing muscles. Some patients may need enteral feeding. For esophageal dysphagia, choice of management depends on the etiology; it may include endoscopic dilation, myotomy, injection of onabotulinumtoxinA (formerly called botulinum toxin type A) for structural abnormalities, or topical steroid therapy for eosinophilic esophagitis.

摘要

吞咽过程分为三个阶段

口腔期、咽期和食管期。口咽性吞咽困难通常是由神经肌肉疾病引起的,如中风和帕金森病,或由药物或放射治疗导致的粘膜干燥引起。食管性吞咽困难通常由食管的解剖缺陷引起,如反流性疾病;动力障碍,如贲门失弛缓症;或嗜酸性食管炎。如果怀疑是口咽性吞咽困难,患者应首先进行水或半固体团块吞咽试验。如果结果呈阳性,可以通过视频荧光吞咽造影检查来确诊。如果怀疑是食管性吞咽困难,患者通常要接受内镜下食管胃十二指肠镜检查。确诊的口咽性吞咽困难的治疗包括短期补偿策略,如改变姿势或食物增稠,以尽量减少误吸的风险。接下来是康复治疗,可能包括生物反馈吞咽练习或吞咽肌肉的电刺激。一些患者可能需要肠内营养。对于食管性吞咽困难,治疗方法的选择取决于病因;可能包括内镜扩张、肌切开术、注射A型肉毒毒素(以前称为A型肉毒杆菌毒素)治疗结构异常,或局部类固醇治疗嗜酸性食管炎。

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