用于法医和亲子鉴定的菲律宾九个微卫星基因座的人口数据库。

Philippine population database at nine microsatellite loci for forensic and paternity applications.

作者信息

Halos S C, Chu J Y, Ferreon A C, Magno M M

机构信息

DNA Analysis Laboratory, University of the Philippines, Diliman, Quezon City, Philippines.

出版信息

Forensic Sci Int. 1999 Apr 12;101(1):27-32. doi: 10.1016/s0379-0738(99)00008-0.

DOI:10.1016/s0379-0738(99)00008-0

PMID:10376334

Abstract

Allele frequency distributions for a Filipino population from the National Capital Region (NCR) were determined for eight STR loci: HUMF13A01, HUMFES/FPS, HUMvWA, HUMFOLP23, HUMD8S306, HUMCSFIPO, HUMTPOX and HUMTHO1; and a VNTR locus: D1S80. Statistical analysis showed that the nine loci showed no deviations from Hardy-Weinberg and linkage equilibrium rules. The average power of paternity exclusion for the nine loci is 0.9962 and the discriminating power is 1-2 x 10(-9). The data obtained from this study will be used as reference data for forensic DNA typing in the Philippines.

摘要

测定了来自国家首都地区（NCR）的菲律宾人群中8个短串联重复序列（STR）基因座：HUMF13A01、HUMFES/FPS、HUMvWA、HUMFOLP23、HUMD8S306、HUMCSFIPO、HUMTPOX和HUMTHO1；以及1个可变数目串联重复序列（VNTR）基因座：D1S80的等位基因频率分布。统计分析表明，这9个基因座均未偏离哈迪-温伯格平衡和连锁平衡规则。这9个基因座的平均父权排除率为0.9962，鉴别力为1 - 2×10⁻⁹。本研究获得的数据将作为菲律宾法医DNA分型的参考数据。