西班牙北部阿拉贡地区六个短串联重复序列位点（HUMTH01、HUMTPOX、HUMCSF1PO、HUMF13A01、HUMFES/FPS、HUMVWFA31）的基因变异情况。

Genetic variation at six STR loci (HUMTH01, HUMTPOX, HUMCSF1PO, HUMF13A01, HUMFES/FPS, HUMVWFA31) in Aragon (north Spain).

作者信息

Martinez Jarreta B, Diaz Roche P, Abecia E

机构信息

Department of Legal Medicine, University of Zaragoza, Spain.

出版信息

Forensic Sci Int. 1999 Mar 15;100(1-2):87-92. doi: 10.1016/s0379-0738(98)00164-9.

DOI:10.1016/s0379-0738(98)00164-9

PMID:10356775

Abstract

The STR loci HUMTH01, HUMPTPOX, HUMCSF1PO, HUMF13A01, HUMFES/FPS and HUMVWFA31 are widely used in forensic casework analyses and population data are necessary to estimate the frequency of a DNA profile. This paper presents the results of a survey aimed to investigate the allele frequency distribution of these loci in an important Spanish population (Aragon, North Spain). Statistical analysis to determine whether allele frequencies were in Hardy-Weinberg Equilibrium was carried out and also to obtain some parameters of medico-legal interest. There was no evidence of association between the alleles of the loci. The Aragonese sample does not differ substantially from other Caucasian populations.

摘要

STR基因座HUMTH01、HUMPTPOX、HUMCSF1PO、HUMF13A01、HUMFES/FPS和HUMVWFA31广泛应用于法医案件分析，而群体数据对于估计DNA图谱的频率是必要的。本文展示了一项调查结果，该调查旨在研究这些基因座在西班牙一个重要群体（西班牙北部阿拉贡）中的等位基因频率分布。进行了统计分析以确定等位基因频率是否处于哈迪-温伯格平衡，同时还获取了一些法医学相关的参数。没有证据表明这些基因座的等位基因之间存在关联。阿拉贡样本与其他高加索人群体没有显著差异。