抗血吸虫化合物（Bilharcid）对曼氏血吸虫的体外和体内作用。
The effect of the antibilharzial compound (Bilharcid) on Schistosoma mansoni in vitro and in vivo.
作者信息
Mahran S G, Shehata H, Abdulla W A, el-Raziky E H
出版信息
Egypt J Bilharz. 1976;3(2):239-45.
The effect of Piperazine diantimonyl tartrate (Bilharcid) as compared with that of tartar emetic on Schistosoma mansoni has been studied. In vitro experiments on living worms in tyrode/serum cultures have proved that Bilharcid 5-10 gamma/ml has the same antibilharzial activity as tartar emetic in 5-10 gamma/ml. In vivo experiments on Schistosoma mansoni infected mice have proved also that Bilharcid has more or less the same effect as that of tartar emetic. In this study, the worm burden load and the oogram techniques were used as the criteria for antibilharzial assessment.
已对酒石酸哌嗪二锑（Bilharcid）与吐酒石对曼氏血吸虫的作用进行了研究。在台氏液/血清培养液中对活虫进行的体外实验证明，5 - 10微克/毫升的Bilharcid与5 - 10微克/毫升的吐酒石具有相同的抗血吸虫活性。对感染曼氏血吸虫的小鼠进行的体内实验也证明，Bilharcid的作用与吐酒石大致相同。在本研究中，虫负荷量和虫卵计数技术被用作抗血吸虫评估的标准。
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