Murray S, Carson K G, Ewings P D, Collins P D, James M A
Department of Cardiology, Taunton and Somerset Hospital, Musgrove Park, Taunton Somerset TA1 5DA, UK.
Heart. 1999 Jul;82(1):89-92. doi: 10.1136/hrt.82.1.89.
To assess the impact of spinal cord stimulation (SCS) on the need for acute admissions for chest pain in patients with refractory angina pectoris.
Retrospective analysis of case records.
19 consecutive patients implanted for SCS between 1987 and 1997. All had three vessel coronary disease, and all were in New York Heart Association functional group III/IV.
Admission rates were calculated for three separate periods: (1) from initial presentation up until last revascularisation; (2) from last revascularisation until SCS implantation; (3) from SCS implantation until the study date. Post-revascularisation rates were then compared with post-SCS rates, without including admissions before revascularisation, as this would bias against revascularisation procedures.
Annual admission rate after revascularisation was 0.97/patient/year, compared with 0.27 after SCS (p = 0.02). Mean time in hospital/patient/year after revascularisation was 8.3 days v 2.5 days after SCS (p = 0.04). No unexplained new ECG changes were observed during follow up and patients presented with unstable angina and acute myocardial infarction in the usual way.
SCS is effective in preventing hospital admissions in patients with refractory angina, without masking serious ischaemic symptoms or leading to silent infarction.
评估脊髓刺激(SCS)对难治性心绞痛患者因胸痛而需急性入院治疗的影响。
病例记录的回顾性分析。
1987年至1997年间连续19例接受SCS植入的患者。所有患者均患有三支血管冠状动脉疾病,且均属于纽约心脏协会功能分级III/IV级。
计算三个不同时间段的入院率:(1)从初次就诊至最后一次血运重建;(2)从最后一次血运重建至SCS植入;(3)从SCS植入至研究日期。然后比较血运重建后的入院率与SCS后的入院率,不包括血运重建前的入院情况,因为这会对血运重建程序产生偏差。
血运重建后的年入院率为0.97/患者/年,而SCS后为0.27(p = 0.02)。血运重建后患者每年的平均住院时间为8.3天,SCS后为2.5天(p = 0.04)。随访期间未观察到无法解释的新心电图变化,患者以通常方式出现不稳定型心绞痛和急性心肌梗死。
SCS可有效预防难治性心绞痛患者的住院治疗,且不会掩盖严重缺血症状或导致无症状梗死。