Zamir D, Amar M, Groisman G, Weiner P
Department of Medicine, Hillel Yaffe Medical Center, Hadera, Israel.
Mayo Clin Proc. 1999 Jun;74(6):575-8. doi: 10.4065/74.6.575.
An opportunistic infection is a known, although under-diagnosed, complication of systemic lupus erythematosus (SLE). A 48-year-old woman with a recent diagnosis of SLE was admitted to the hospital because of a fever, confused state, and convulsive episode. Her symptoms were interpreted as being compatible with lupus cerebritis. Treatment with methylprednisolone resulted in a temporary improvement in the patient's condition. Nevertheless, during the next few weeks, her physical and mental condition deteriorated, and she died of massive pulmonary emboli. An autopsy revealed no signs of lupus cerebritis; however, disseminated cerebral toxoplasmosis was found. Cerebral toxoplasmosis is a rare complication of SLE that may be misdiagnosed as lupus cerebritis.
机会性感染是系统性红斑狼疮（SLE）一种已知但诊断不足的并发症。一名近期诊断为SLE的48岁女性因发热、意识模糊状态和惊厥发作入院。她的症状被解释为符合狼疮性脑病。甲基泼尼松龙治疗使患者病情暂时改善。然而，在接下来的几周内，她的身体和精神状况恶化，最终死于大面积肺栓塞。尸检未发现狼疮性脑病的迹象；然而，发现了播散性脑弓形虫病。脑弓形虫病是SLE的一种罕见并发症，可能被误诊为狼疮性脑病。
