Hart S, Skinner E C, Meyerowitz B E, Boyd S, Lieskovsky G, Skinner D G
Department of Psychiatry, Stanford University School of Medicine, California, USA.
J Urol. 1999 Jul;162(1):77-81. doi: 10.1097/00005392-199907000-00019.
Radical cystectomy for bladder cancer is associated with many changes in bodily function with sexual and urinary dysfunction most prevalent. However, little research has been done on how efforts to improve erectile function relate to quality of life. Also, the psychological benefits associated with continent urinary diversion have not been fully explored. We compared long-term quality of life outcomes among 3 urinary diversion groups, and between patients who had and had not received an inflatable penile prosthesis.
The 224 participating patients completed 4 self-reporting questionnaires, including the profile of mood states, and adapted versions of the sexual history form, body image dissatisfaction scale and quality of life questionnaire. We compared self-reports of emotional distress, global quality of life, sexuality, body image dissatisfaction, urinary diversion problems, and problems with social, physical and functional activities in patients with advanced bladder cancer who underwent urinary diversion, including an ileal conduit in 25, cutaneous Kock pouch in 93 and urethral Kock pouch in 103. Patients who had or had not received an inflatable penile prosthesis after cystectomy were also compared in regard to quality of life variables.
Regardless of type of urinary diversion the majority of patients reported good overall quality of life, little emotional distress and few problems with social, physical or functional activities. Problems with urinary diversion and sexual functioning were identified as most common. After controlling for age analysis of variance showed no significant differences among urinary diversion subgroups in any quality of life area. However, t tests controlling for age indicated that penile prosthesis placement was significantly associated with better sexual function and satisfaction.
Quality of life appears good in these long-term survivors of advanced bladder cancer. The type of urinary diversion does not appear to be associated with differential quality of life. Findings suggest that physicians may wish to discuss urinary diversion problems and sexual dysfunction as long-term correlates of radical cystectomy for bladder cancer. Furthermore, they may also wish to discuss the option of erectile aids in men with erectile dysfunction after cystectomy.
膀胱癌根治性膀胱切除术会导致身体功能发生诸多变化,其中性功能和排尿功能障碍最为常见。然而,关于改善勃起功能的努力与生活质量之间的关系,相关研究甚少。此外,可控性尿流改道所带来的心理益处也尚未得到充分探究。我们比较了3种尿流改道组的长期生活质量结果,以及接受和未接受可膨胀阴茎假体的患者之间的生活质量结果。
224名参与研究的患者完成了4份自我报告问卷,包括情绪状态量表,以及性病史表格、身体形象不满量表和生活质量问卷的改编版本。我们比较了晚期膀胱癌患者在接受尿流改道后,包括25例行回肠膀胱术、93例行皮肤可控性膀胱术和103例行尿道可控性膀胱术患者的情绪困扰、总体生活质量、性功能、身体形象不满、尿流改道问题以及社交、身体和功能活动方面的问题的自我报告。还比较了膀胱切除术后接受或未接受可膨胀阴茎假体的患者在生活质量变量方面的情况。
无论尿流改道类型如何,大多数患者报告总体生活质量良好,情绪困扰较少,社交、身体或功能活动方面的问题也较少。尿流改道和性功能问题被认为是最常见的。在控制年龄后,方差分析显示尿流改道亚组在任何生活质量领域均无显著差异。然而,控制年龄的t检验表明,阴茎假体植入与更好的性功能和满意度显著相关。
这些晚期膀胱癌长期幸存者的生活质量似乎良好。尿流改道类型似乎与不同的生活质量无关。研究结果表明,医生可能希望讨论尿流改道问题和性功能障碍,作为膀胱癌根治性膀胱切除术的长期相关问题。此外,他们可能还希望讨论膀胱切除术后勃起功能障碍男性使用勃起辅助装置的选择。