Carlsson L, Johansson C
Dept of Orthopaedics, Gothenburg University, Sahlgrenska Universitetssjukhuset, Göteborg, Sweden.
Lakartidningen. 1999 May 19;96(20):2458-60, 2463-7.
Advances in our knowledge of multfactorial host-biomaterial interactions have improved the outcome of joint replacement surgery. Fixation and aseptic loosening are the principal foci of research. Wear debris from articulating parts is a major cause of prosthetic loosening. Tribological analysis, and the development of new materials and surface finishes have reduced wear particle production. The use of modular implants increases flexibility and facilitates surgical fit, but also introduces new problems such as dissociation of components, corrosion and wear. In the future, as design, biomaterials and surgical technique become further optimised, arthroplasty may also become an alternative for use in younger patients.
我们对多因素宿主-生物材料相互作用的认识取得进展，改善了关节置换手术的效果。固定和无菌性松动是研究的主要重点。关节部件产生的磨损碎屑是假体松动的主要原因。摩擦学分析以及新材料和表面处理技术的发展减少了磨损颗粒的产生。模块化植入物的使用增加了灵活性并便于手术安装，但也带来了诸如部件分离、腐蚀和磨损等新问题。未来，随着设计、生物材料和手术技术进一步优化，关节成形术也可能成为年轻患者的一种选择。
