血管紧张素与脑血流量。
Angiotensin and cerebral blood flow.
作者信息
Saavedra J M, Nishimura Y
机构信息
Section on Pharmacology, National Institute of Mental Health, Bethesda, Maryland 20892-1264, USA.
出版信息
Cell Mol Neurobiol. 1999 Oct;19(5):553-73. doi: 10.1023/a:1006995016403.
Abstract
1.General properties of the cerebral circulation. 2.Cerebral blood flow autoregulation in hypertension, in stroke, and during the aging process. 3.The Angiotensin system. 4.Angiotensin receptor subtypes. 5.Angiotensin receptors and actions of Angiotensin II in the brain: interactions between the brain and circulating Angiotensin II. 6.The cerebrovascular Angiotensin system. 7.Effects of Angiotensin II on cerebrovascular reactivity. 8.Angiotensin and cerebrovascular flow. 9.Effects of therapeutic modulation of the Angiotensin II system on cerebrovascular regulation in health and disease. 10.Conclusions.
摘要
- 脑循环的一般特性。2. 高血压、中风及衰老过程中的脑血流自动调节。3. 血管紧张素系统。4. 血管紧张素受体亚型。5. 血管紧张素受体与脑中血管紧张素II的作用：脑与循环血管紧张素II之间的相互作用。6. 脑血管紧张素系统。7. 血管紧张素II对脑血管反应性的影响。8. 血管紧张素与脑血流。9. 血管紧张素II系统治疗性调节对健康和疾病状态下脑血管调节的影响。10. 结论。
相似文献
1
Angiotensin and cerebral blood flow.血管紧张素与脑血流量。
Cell Mol Neurobiol. 1999 Oct;19(5):553-73. doi: 10.1023/a:1006995016403.
2
Blockade of the renin-angiotensin system improves cerebral microcirculatory perfusion in diabetic hypertensive rats.阻断肾素-血管紧张素系统可改善糖尿病高血压大鼠的脑微循环灌注。
Microvasc Res. 2013 May;87:41-9. doi: 10.1016/j.mvr.2013.02.007. Epub 2013 Mar 1.
3
Regional hemodynamic effects of candesartan cilexetil (TCV-116), an angiotensin II AT1-receptor antagonist, in conscious spontaneously hypertensive rats.血管紧张素II AT1受体拮抗剂坎地沙坦酯（TCV-116）对清醒自发性高血压大鼠的局部血流动力学影响。
Jpn J Pharmacol. 1997 Mar;73(3):185-90. doi: 10.1254/jjp.73.185.
4
Blocking the tissue renin-angiotensin system: the future cornerstone of therapy.阻断组织肾素-血管紧张素系统：未来治疗的基石
J Hum Hypertens. 2000 Oct;14 Suppl 2:S23-31. doi: 10.1038/sj.jhh.1001070.
5
Protective effects of candesartan cilexetil (TCV-116) against stroke, kidney dysfunction and cardiac hypertrophy in stroke-prone spontaneously hypertensive rats.坎地沙坦酯（TCV-116）对易卒中自发性高血压大鼠的卒中、肾功能障碍及心脏肥大的保护作用
Clin Exp Hypertens. 1997 Oct;19(7):1079-99. doi: 10.3109/10641969709083206.
6
[Organ protection by angiotensin II receptor blockers].
Nihon Rinsho. 2004 Mar;62 Suppl 3:569-73.
7
Hypertension control among African Americans: an urgent call for action.非裔美国人的高血压控制：紧急行动呼吁
J Clin Hypertens (Greenwich). 2004 Jun;6(6):333-4. doi: 10.1111/j.1524-6175.2004.03626.x.
8
Inhibition of vascular angiotensin-converting enzyme by telmisartan via the peroxisome proliferator-activated receptor gamma agonistic property in rats.替米沙坦通过过氧化物酶体增殖物激活受体γ激动特性对大鼠血管紧张素转换酶的抑制作用。
Hypertens Res. 2007 Dec;30(12):1231-7. doi: 10.1291/hypres.30.1231.
9
Renal responses to angiotensin receptor antagonist and angiotensin-converting enzyme inhibitor in partially nephrectomized spontaneously hypertensive rats.部分肾切除的自发性高血压大鼠对血管紧张素受体拮抗剂和血管紧张素转换酶抑制剂的肾脏反应。
J Cardiovasc Pharmacol. 1995 Oct;26(4):564-9. doi: 10.1097/00005344-199510000-00009.
10
Angiotensin II receptor antagonist CV-11974 and cerebral blood flow autoregulation.血管紧张素II受体拮抗剂CV-11974与脑血流自动调节
J Hypertens. 1995 Jul;13(7):755-61.
引用本文的文献
1
Correlation Between Angiotensin Receptor Type 1 Polymorphisms and Atherosclerotic Cerebral Infarction Risk.血管紧张素1型受体多态性与动脉粥样硬化性脑梗死风险的相关性
Pharmgenomics Pers Med. 2022 May 11;15:477-485. doi: 10.2147/PGPM.S364648. eCollection 2022.
2
Thomas Willis Lecture: Targeting Brain Arterioles for Acute Stroke Treatment.托马斯·威利斯讲座：急性脑卒中治疗的靶向脑动脉。
Stroke. 2021 Jul;52(7):2465-2477. doi: 10.1161/STROKEAHA.121.034620. Epub 2021 Jun 9.
3
Neuroprotective Effects of Casein-Derived Peptide Met-Lys-Pro (MKP) in a Hypertensive Model.酪蛋白衍生肽Met-Lys-Pro（MKP）在高血压模型中的神经保护作用
Front Neurosci. 2020 Aug 14;14:845. doi: 10.3389/fnins.2020.00845. eCollection 2020.
4
ACE (Angiotensin-Converting Enzyme) Inhibition Reverses Vasoconstriction and Impaired Dilation of Pial Collaterals in Chronic Hypertension.血管紧张素转换酶（ACE）抑制逆转慢性高血压患者软脑膜侧支血管收缩和舒张功能障碍。
Hypertension. 2020 Jul;76(1):226-235. doi: 10.1161/HYPERTENSIONAHA.119.14315. Epub 2020 May 18.
5
Is the Brain an Early or Late Component of Essential Hypertension?大脑是原发性高血压的早期还是晚期发病因素？
Am J Hypertens. 2020 May 21;33(6):482-490. doi: 10.1093/ajh/hpaa038.
6
The importance of comorbidities in ischemic stroke: Impact of hypertension on the cerebral circulation.合并症在缺血性脑卒中的重要性：高血压对脑循环的影响。
J Cereb Blood Flow Metab. 2018 Dec;38(12):2129-2149. doi: 10.1177/0271678X18800589. Epub 2018 Sep 10.
7
Neonatal cerebrovascular autoregulation.新生儿脑血管自动调节。
Pediatr Res. 2018 Nov;84(5):602-610. doi: 10.1038/s41390-018-0141-6. Epub 2018 Sep 8.
8
Transgenic Mice Overexpressing Human Angiotensin I Receptor Gene Are Susceptible to Stroke Injury.过表达人血管紧张素I受体基因的转基因小鼠易患中风损伤。
Mol Neurobiol. 2016 Apr;53(3):1533-1539. doi: 10.1007/s12035-015-9109-2. Epub 2015 Feb 5.
9
Association of gene variants of the renin-angiotensin system with accelerated hippocampal volume loss and cognitive decline in old age.肾素-血管紧张素系统基因变异与老年海马体体积加速减少及认知衰退的关联
Am J Psychiatry. 2014 Nov 1;171(11):1214-21. doi: 10.1176/appi.ajp.2014.13111543.
10
Antihypertensive therapy and cerebral hemodynamics in executive mild cognitive impairment: results of a pilot randomized clinical trial.抗高血压治疗与执行轻度认知障碍患者的脑血流动力学：一项初步随机临床试验结果。
J Am Geriatr Soc. 2013 Feb;61(2):194-201. doi: 10.1111/jgs.12100. Epub 2013 Jan 25.
本文引用的文献
1
Structural analysis and regulation of angiotensin II receptors.血管紧张素 II 受体的结构分析与调控。
Trends Endocrinol Metab. 1994 Jan-Feb;5(1):28-35. doi: 10.1016/1043-2760(94)90118-x.
2
The angiotensin AT1 receptor antagonist CV-11974 regulates cerebral blood flow and brain angiotensin AT1 receptor expression.血管紧张素AT1受体拮抗剂CV-11974可调节脑血流量及脑内血管紧张素AT1受体的表达。
Basic Res Cardiol. 1998;93 Suppl 2:63-8. doi: 10.1007/s003950050221.
3
Attenuation and recovery of brain stem autoregulation in spontaneously hypertensive rats.自发性高血压大鼠脑干自动调节功能的减弱与恢复
J Cereb Blood Flow Metab. 1998 Mar;18(3):305-10. doi: 10.1097/00004647-199803000-00009.
4
Protective effects of candesartan cilexetil (TCV-116) against stroke, kidney dysfunction and cardiac hypertrophy in stroke-prone spontaneously hypertensive rats.坎地沙坦酯（TCV-116）对易卒中自发性高血压大鼠的卒中、肾功能障碍及心脏肥大的保护作用
Clin Exp Hypertens. 1997 Oct;19(7):1079-99. doi: 10.3109/10641969709083206.
5
Effect of enalapril maleate on cerebral blood flow in patients with chronic heart failure.马来酸依那普利对慢性心力衰竭患者脑血流量的影响。
Angiology. 1997 Aug;48(8):707-13. doi: 10.1177/000331979704800806.
6
Characterization of angiotensin-II effects on cerebral and ocular circulation by noninvasive methods.通过非侵入性方法对血管紧张素 II 对脑循环和眼循环的影响进行表征。
Br J Clin Pharmacol. 1997 May;43(5):501-8. doi: 10.1046/j.1365-2125.1997.00585.x.
7
Cerebrovascular changes in chronic hypertension. Protective effects of enalapril in rats.慢性高血压中的脑血管变化。依那普利对大鼠的保护作用。
Stroke. 1997 May;28(5):1028-34. doi: 10.1161/01.str.28.5.1028.
8
Angiotensin II-generating system in dog and monkey ocular tissues.犬和猴眼组织中的血管紧张素II生成系统。
Clin Exp Pharmacol Physiol. 1997 Mar-Apr;24(3-4):243-8. doi: 10.1111/j.1440-1681.1997.tb01814.x.
9
Cerebral blood flow of the exposed brain surface measured by laser Doppler perfusion imaging.通过激光多普勒灌注成像测量暴露脑表面的脑血流量。
Acta Physiol Scand. 1997 Jan;159(1):15-22. doi: 10.1046/j.1365-201X.1997.560333000.x.
10
Angiotensin II- and IV-induced changes in cerebral blood flow. Roles of AT1, AT2, and AT4 receptor subtypes.血管紧张素II和IV诱导的脑血流变化。AT1、AT2和AT4受体亚型的作用。
Regul Pept. 1997 Jan 29;68(2):131-8. doi: 10.1016/s0167-0115(96)02116-7.
Zotero 插件