Robinson J B, Im D D, Logan L, McGuire W P, Rosenshein N B
Gynecologic Oncology Center, Mercy Medical Center, Baltimore, Maryland 21202, USA.
Gynecol Oncol. 1999 Jul;74(1):123-7. doi: 10.1006/gyno.1999.5375.
The aim of this study was to report a case of extraovarian granulosa cell tumor and to describe its relevance to the histologic origin of granulosa cell tumors and to clinical practice.
The clinical course and histopathology of the case were reviewed, and a literature search for other reported cases was performed.
A 67-year-old woman presented with postmenopausal bleeding and a pelvic mass. Laparotomy revealed a 16-cm mass arising from the right pelvic sidewall, filling the pelvis, and involving the bladder and rectosigmoid colon. Both ovaries appeared normal and were separate from the mass. Pathologic examination revealed granulosa cell tumor. A literature search revealed no recently reported cases of extraovarian granulosa cell tumor.
Granulosa cell tumors can arise in locations other than the ovary and may be derived from the mesenchyme of the genital ridge. Women who have undergone oophorectomy may have the potential to develop granulosa cell tumors.
本研究旨在报告一例卵巢外颗粒细胞瘤病例，并描述其与颗粒细胞瘤组织学起源及临床实践的相关性。
回顾该病例的临床病程及组织病理学情况，并对其他已报道病例进行文献检索。
一名67岁女性因绝经后出血及盆腔肿物就诊。剖腹探查发现一个16厘米的肿物，起源于右盆腔侧壁，充满盆腔，并累及膀胱和乙状结肠直肠。双侧卵巢外观正常，与肿物分离。病理检查显示为颗粒细胞瘤。文献检索未发现近期报道的卵巢外颗粒细胞瘤病例。
颗粒细胞瘤可发生于卵巢以外的部位，可能起源于生殖嵴的间充质。接受过卵巢切除术的女性可能有发生颗粒细胞瘤的潜在风险。
