Naniwadekar Manjiri R, Patil N J
Department of Pathology, Krishna Institute of Medical Sciences University, Karad 415110, India.
Patholog Res Int. 2010 Mar 4;2010:292606. doi: 10.4061/2010/292606.
Extraovarian granulosa cell tumor (GCT) is a very uncommon tumor, assumed to arise from the ectopic gonadal tissue along the embryonal route of the genital ridge. A 54 years old female patient presented with a mass and acute pain in abdomen. Exploratory laparatomy revealed hemoperitoneum with a large mesenteric mass measuring 13 × 12 cm in size, showing extensive areas of haemorrhages. Histopathological examination of the excised mass showed features of adult-type GCT. As the patient had a history of hysterectomy with bilateral salpingo-oophorectomy 10 years ago for ''leiomyoma" with no evidence of GCT of the ovary in the histopathology report, a diagnosis of extraovarian GCT was made. A diagnosis of extraovarian GCT should be carried out after excluding any previous history of GCT of the ovary. Tumor rupture with haemoperitoneum is a well-known complication of GCT. Extraovarian GCT is a rare tumor with only 10 cases reported in literature. The case is presented for its rarity.
卵巢外颗粒细胞瘤（GCT）是一种非常罕见的肿瘤，被认为起源于沿生殖嵴胚胎路径的异位性腺组织。一名54岁女性患者出现腹部肿块和急性疼痛。剖腹探查发现腹腔积血，有一个大小为13×12厘米的大肠系膜肿块，有广泛的出血区域。切除肿块的组织病理学检查显示为成人型GCT特征。由于该患者10年前因“平滑肌瘤”行子宫切除术及双侧输卵管卵巢切除术，组织病理学报告中无卵巢GCT证据，故诊断为卵巢外GCT。卵巢外GCT的诊断应在排除既往卵巢GCT病史后进行。肿瘤破裂伴腹腔积血是GCT的一种众所周知的并发症。卵巢外GCT是一种罕见肿瘤，文献中仅报道了10例。现展示该病例因其罕见性。
