Alessandrini M, Giacomini P, Sorace F, Bruno E
Università degli Studi di Roma Tor Vergata, Clinica Otorinolaringoiatrica.
Acta Otorhinolaryngol Ital. 1998 Dec;18(6):368-72.
Today the canal/cupulolithiasic pathogenesis of benign paroxysmal positional vertigo (BPPV) appears well defined; what is less clear is the origin of the postural "instability" often associated with rotatory vertigo. This form is less marked but still resists all know treatments. The purpose of the present study was to determine the actual postural arrangement of subjects suffering from canalolithiasis (CL) of the posterior semicircular canal (PSC) both before and after the positioning maneuver. In this case a personal method of spectral frequency analysis was used in an attempt to clarify the origin of the residual "instability" following otolithic repositioning. Static posturographic testing was performed on 20 patients with CL of the PSC and another 20 normal subjects of comparable age. In the present study the repositioning maneuver leads to a reduction in latero-lateral oscillation without any anterior-posterior variation. Such stabilization covers all the frequencies if a visual input is also present while it is limited to the lower frequencies when the visual content is lacking. In fact, in the latter case the subject maintains his posture using only vestibular and proprioceptive input. On the other hand, the anterior-posterior oscillations increase in all frequency ranges and this increase remains essentially unchanged after the repositioning maneuver. The authors feel that the anterior-posterior destabilization seen in CL of the PSC may stem from a proprioceptive-macular alteration linked to otolitic detachment rather than abnormal ampullar stimulation. The persistence and residual postural alterations found could, therefore, explain the persistent sense of instability that CL patients often complain of, even after the maneuvers which have encountered such success in controlling BPPV.
如今,良性阵发性位置性眩晕(BPPV)的半规管/嵴帽结石症发病机制似乎已明确;但与旋转性眩晕相关的姿势“不稳定”的起源尚不清楚。这种形式不太明显,但仍对所有已知治疗方法均有抵抗。本研究的目的是确定后半规管(PSC)管结石症(CL)患者在定位操作前后的实际姿势排列。在这种情况下,使用了一种个人频谱频率分析方法,试图阐明耳石复位后残留“不稳定”的起源。对20例PSC管结石症患者和另外20名年龄相仿的正常受试者进行了静态姿势描记测试。在本研究中,复位操作导致左右摆动减少,而前后无变化。如果同时存在视觉输入,这种稳定作用涵盖所有频率;而当缺乏视觉内容时,稳定作用仅限于较低频率。事实上,在后一种情况下,受试者仅使用前庭和本体感觉输入来维持姿势。另一方面,前后摆动在所有频率范围内均增加且在复位操作后基本保持不变。作者认为,PSC管结石症中所见的前后不稳定可能源于与耳石脱离相关的本体感觉 - 黄斑改变,而非壶腹异常刺激。因此,所发现的持续性和残留姿势改变可以解释CL患者即使在控制BPPV取得成功的操作后仍经常抱怨的持续不稳定感。