Donly K J, Grandgenett C
Department of Pediatric Dentistry, University of Texas Health Science Center at San Antonio 78284, USA.
Am J Dent. 1998 Oct;11(5):245-8.
To examine the in vitro caries inhibition of a resin-modified glass ionomer cement (Vitremer-3M) and two compomers (Dyract-Dentsply; Compoglass-Ivoclar).
Standardized Class V preparations were placed in 40 molars, the gingival margin placed below the cementoenamel junction. Randomly, 10 Vitremer, 10 Dyract and 10 Compoglass restorations were placed according to manufacturer's instructions, in 30 teeth. Ten teeth received P-50 composite resin (3M) restorations and acted as the control. All teeth had an acid-resistant varnish placed to within 1 mm of restoration margins and they were then placed into artificial saliva for 4 weeks, the saliva being replenished every 48 hours. All teeth were subjected to an artificial caries challenge (pH 4.4) for 5 days. Sections of 100 microns were obtained, photographed under polarized light microscopy, and then digitized to quantitate demineralized areas adjacent to the restoration.
The mean (+/- S.D) area (microns 2) demineralization 100 microns from the dentin/gingival margin was: Vitremer 4965 +/- 841, Compoglass 4981 +/- 2209, Dyract 5375 +/- 516, P-50 8088 +/- 2083. ANOVA and Duncan's (P < 0.05) indicated all three fluoride-releasing materials examined in this study had significantly less demineralization adjacent to restoration margins than the P-50 composite resin control. Seventy percent of glass ionomer cement restorations demonstrated adjacent dentin inhibition zones, while no dentin inhibition zones were demonstrated with the compomer restorations.
研究树脂改性玻璃离子水门汀（Vitremer - 3M）和两种复合体（Dyract - Dentsply；Compoglass - Ivoclar）的体外防龋效果。
在40颗磨牙上制备标准化的V类洞，龈缘置于牙骨质釉质界下方。随机地，按照制造商的说明，在30颗牙齿中分别置入10个Vitremer、10个Dyract和10个Compoglass修复体。10颗牙齿接受P - 50复合树脂（3M）修复体作为对照。所有牙齿均在修复边缘内1毫米处涂布耐酸漆，然后置于人工唾液中4周，每48小时更换一次唾液。所有牙齿均接受5天的人工龋损挑战（pH 4.4）。获取100微米厚的切片，在偏光显微镜下拍照，然后数字化以定量修复体邻近的脱矿区域。
距牙本质/龈缘100微米处脱矿的平均（±标准差）面积（平方微米）为：Vitremer 4965±841，Compoglass 4981±2209，Dyract 5375±516，P - 50 8088±2083。方差分析和邓肯检验（P < 0.05）表明，本研究中检测的所有三种释氟材料在修复边缘邻近区域的脱矿明显少于P - 50复合树脂对照。70%的玻璃离子水门汀修复体显示出邻近牙本质的抑制区，而复合体修复体未显示出牙本质抑制区。
