Department of Paediatric and Preventive Dentistry, Faculty of Dental Medicine, University Ss. Cyril and Methodius Skopje, Skopje, Republic of Macedonia.
J Mater Sci Mater Med. 2012 Jul;23(7):1811-21. doi: 10.1007/s10856-012-4653-z. Epub 2012 Apr 25.
This study was carried out in order to determine the extent to which ions released from fluoride-containing dental restoratives migrated through the enamel and dentine of extracted teeth. A total of 40 permanent human 3rd molars were used. They were extracted for orthodontic reasons, and employed within 1 month of extraction. A cervical (Class V) cavity was prepared in each tooth, then filled with one of: a conventional glass-ionomer, a resin-modified glass-ionomer, a polyacid-modified composite resin ("compomer") or a fluoride-releasing resin composite. Ten samples were prepared per material. After 1 month, five specimens per material were prepared and examined under SEM/EDX. Concentrations of sodium, aluminium, strontium, fluorine, magnesium, silicon, phosphorus and calcium were determined within the tooth. After 18 months, the remaining five specimens for each material were prepared and studied in the same way. The greatest extent of ion migration into the tooth was found with the conventional glass-ionomer and least migration was found for the fluoride-releasing composite, which showed no evidence of fluoride migration at all. Levels of migrating ions were generally higher in the 18 month specimens than in the 1 month specimens, and also higher in the dentine than in the enamel. Ions released by restorative dental materials have been shown conclusively for the first time to be capable of migrating into the enamel and dentine surrounding the restoration. The conventional glass-ionomer showed the highest level of ion migration whereas the fluoridated composite resin showed little if any ion migration. This suggests that the conventional glass-ionomer has the greatest caries inhibiting effects of all the materials tested, and the fluoridated composite the least.
本研究旨在确定从含氟牙科修复体中释放的离子通过提取牙齿的牙釉质和牙本质迁移的程度。共使用了 40 颗永久的人类第三磨牙。它们因正畸原因而被拔出，并在拔出后 1 个月内使用。在每颗牙齿上制备一个颈部（V 类）腔，然后用以下材料之一填充：传统的玻璃离子体、树脂改性的玻璃离子体、多酸改性的复合树脂（“复合树脂”）或释放氟的树脂复合树脂。每种材料制备 10 个样本。1 个月后，每种材料制备 5 个样本，并在 SEM/EDX 下检查。在牙齿内测定钠、铝、锶、氟、镁、硅、磷和钙的浓度。18 个月后，对每种材料的其余 5 个样本进行同样的准备和研究。发现传统玻璃离子体的离子迁移到牙齿中的程度最大，而释放氟的复合材料的迁移程度最小，完全没有证据表明氟迁移。与 1 个月样本相比，18 个月样本中的迁移离子水平普遍较高，而且在牙本质中的水平也高于牙釉质。修复牙科材料释放的离子首次被证明能够迁移到修复体周围的牙釉质和牙本质中。传统的玻璃离子体显示出最高水平的离子迁移，而含氟复合树脂则显示出很少甚至没有离子迁移。这表明传统的玻璃离子体在所有测试材料中具有最大的抑制龋齿效果，而含氟复合树脂则最小。
