Seta T, Yokosuka O
First Department of Medicine, Chiba University School of Medicine.
Nihon Rinsho. 1999 Jun;57(6):1305-9.
Recently, a novel hepatitis related virus was described and named as TTV. The positive rates of TTV DNA in healthy subjects to far reported ranged from 1% to 62%, therefore, there must be large differences in the prevalence of TTV in healthy subjects from country to country. However, detailed data are lacking in many reports, care should be taken in analyzing them. Generally, elderly subjects tend to have increased positivity in the same area. Sanitary environment may influence the positive rate. In addition the distribution of genotype may influence the positive rate. Although the high prevalence of TTV in healthy subjects may indicate the TTV as non-hepatopathogenic virus, further studies will be needed before drawing the conclusion.
最近,一种新型肝炎相关病毒被发现并命名为TTV。目前报道的健康人群中TTV DNA的阳性率在1%至62%之间,因此,不同国家健康人群中TTV的流行率肯定存在很大差异。然而,许多报告缺乏详细数据,在分析这些数据时应谨慎。一般来说,在同一地区,老年受试者的阳性率往往会增加。卫生环境可能会影响阳性率。此外,基因型的分布也可能影响阳性率。尽管健康人群中TTV的高流行率可能表明TTV是非致病性肝炎病毒,但在得出结论之前还需要进一步研究。