[急性肝炎患者中的TT病毒（TTV）感染]

[TT virus(TTV) infection in patients with acute hepatitis].

作者信息

Hayashi K, Fukuda Y, Hayakawa T, Kumada T, Nakano S

机构信息

Second Department of Internal Medicine, Nagoya University School of Medicine.

出版信息

Nihon Rinsho. 1999 Jun;57(6):1322-5.

PMID:10390991

Abstract

A novel DNA virus, TT virus(TTV), has been reported in patients with posttransfusion hepatitis of unknown etiology. However association between TTV and acute hepatitis has not been shown. We investigated the prevalence of TTV in acute hepatitis. TTV-positive rates in acute hepatitis A, B, C, cytomegalovirus infection, Epstein-Barr virus infection, and acute hepatitis of unknown etiology were 15.3%, 21.8%, 60.0%, 0%, 10.0%, 22.6%, respectively. There were no significant differences in TTV prevalence between each etiology and healthy blood donors(20.8%). Clinical data were similar between patients with or without TTV. In this study we could not find any difference in the prevalence of TTV between acute hepatitis with known etiologies and that with unknown etiology. TTV did not affect the clinical features of acute hepatitis with known etiologies.

摘要

一种新型DNA病毒，即TT病毒（TTV），已在病因不明的输血后肝炎患者中被报道。然而，TTV与急性肝炎之间的关联尚未得到证实。我们调查了急性肝炎中TTV的流行情况。甲型、乙型、丙型急性肝炎、巨细胞病毒感染、EB病毒感染以及病因不明的急性肝炎中TTV阳性率分别为15.3%、21.8%、60.0%、0%、10.0%、22.6%。各病因组与健康献血者（20.8%）的TTV流行率无显著差异。有或无TTV的患者临床资料相似。在本研究中，我们未发现已知病因的急性肝炎与病因不明的急性肝炎在TTV流行率上有任何差异。TTV不影响已知病因的急性肝炎的临床特征。