Safi H J, Miller C C
Department of Surgery, Baylor College of Medicine, Houston, Texas 77030, USA.
Ann Thorac Surg. 1999 Jun;67(6):1937-9; discussion 1953-8. doi: 10.1016/s0003-4975(99)00397-5.
During simple cross-clamp repair of the descending thoracic or thoracoabdominal aorta, the likelihood of neurologic complications increases greatly after only 30 minutes of spinal cord ischemia. At greatest risk are patients with type II thoracoabdominal aortic aneurysms.
We reviewed our experience of simple cross-clamp repair and procedures accompanied by adjuncts, paying particular attention to the outcome of patients who had type II thoracoabdominal aortic aneurysms. Between February 1991 and March 1998, 508 patients had descending thoracic and thoracoabdominal aortic repair, 255 (50.2%) of whom received the adjuncts of cerebrospinal fluid drainage and distal aortic perfusion.
Fifteen patients died on the day of operation and could not be evaluated for neurologic deficit. The overall incidence of neurologic deficit was 33 of 493 patients (6.7%). In patients who received adjuncts, neurologic deficit occurred in 9 of 247 (3.6%) overall; in types I and II it was 8 of 164 (4.9%), and in type II alone, 7 of 87 (8.1%). Neurologic deficit in simple cross-clamp patients was 24 of 246 (9.8%) overall; in types I and II it was 15 of 99 (15.2%), and in type II alone, 13 of 44 (29.6%).
With the surgical adjuncts of cerebrospinal fluid drainage and distal aortic perfusion, the probability of neurologic deficit is lowered appreciably.
在胸降主动脉或胸腹主动脉的单纯交叉钳夹修复过程中,脊髓缺血仅30分钟后,神经并发症的可能性就会大幅增加。II型胸腹主动脉瘤患者的风险最高。
我们回顾了单纯交叉钳夹修复及辅助手术的经验,特别关注II型胸腹主动脉瘤患者的治疗结果。1991年2月至1998年3月期间,508例患者接受了胸降主动脉和胸腹主动脉修复,其中255例(50.2%)接受了脑脊液引流和远端主动脉灌注辅助治疗。
15例患者在手术当天死亡,无法评估神经功能缺损情况。493例患者中,神经功能缺损的总体发生率为33例(6.7%)。接受辅助治疗的患者中,247例中有9例(3.6%)出现神经功能缺损;I型和II型中,164例中有8例(4.9%),仅II型中,87例中有7例(8.1%)。单纯交叉钳夹患者中,神经功能缺损总体发生率为246例中的24例(9.8%);I型和II型中,99例中有15例(15.2%),仅II型中,44例中有13例(29.6%)。
采用脑脊液引流和远端主动脉灌注的手术辅助手段,可明显降低神经功能缺损的概率。