Lopez-Marco Ana, Adams Benjamin, Oo Aung Ye
Department of Cardiac Surgery, St Bartholomew's Hospital, London, United Kingdom.
JTCVS Tech. 2020 Jun 25;3:25-36. doi: 10.1016/j.xjtc.2020.06.028. eCollection 2020 Sep.
Open surgical repair remains the gold standard for treatment of thoracoabdominal aortic aneurysm (TAAA). Surgery aims to replace the whole length of the diseased distal aorta while protecting the spinal cord and the visceral organs to limit ischemia-related complications. The substantial associated surgical risks, including death, paraplegia, renal failure requiring permanent dialysis, and respiratory complications leading to prolonged intensive care unit stay, still outweigh the natural history of TAAA with conservative treatment.
We describe in detail our current approach to open extent II TAAA repair with a step-by-step illustration of the technique and the surgical adjuncts.
We routinely perform left heart bypass with mild passive hypothermia (34°C), cerebrospinal fluid drainage, sequential aortic cross-clamping, monitoring of motor evoked potentials (MEPs) and cerebral, paraspinal, and lower limb oxygen saturation by near-infrared spectrometry, as well as selective visceral perfusion via the celiac and superior mesenteric arteries and renal protection with intermittent administration of Custodiol HTK (histidine-tryptophan-ketoglutarate) solution via the renal arteries. We advocate for individual branch reimplantation using a branched thoracoabdominal graft when possible, and we selectively reattach 1 or more pairs of the lower thoracic intercostal arteries and/or high lumbar arteries, even in the absence of a significant reduction in the MEPs signal. The distal anastomosis is usually constructed above the aortic bifurcation and occasionally to each iliac separately using a bifurcated graft.
Favorable early outcomes and a durable TAAA repair can be achieved at experienced high-volume centers with standardized preoperative selection and multidisciplinary team-based intraoperative and postoperative management of these patients.
开放手术修复仍然是胸腹主动脉瘤(TAAA)治疗的金标准。手术旨在替换病变远端主动脉的全长,同时保护脊髓和内脏器官以限制缺血相关并发症。包括死亡、截瘫、需要永久性透析的肾衰竭以及导致重症监护病房住院时间延长的呼吸并发症在内的重大相关手术风险,仍然超过了TAAA保守治疗的自然病程。
我们详细描述了目前开放II型TAAA修复的方法,并对技术和手术辅助措施进行了分步说明。
我们常规进行轻度被动低温(34°C)下的左心旁路、脑脊液引流、序贯性主动脉交叉钳夹、通过运动诱发电位(MEP)监测以及通过近红外光谱法监测大脑、椎旁和下肢的氧饱和度,以及通过腹腔干和肠系膜上动脉进行选择性内脏灌注,并通过肾动脉间歇性给予Custodiol HTK(组氨酸-色氨酸-酮戊二酸)溶液进行肾脏保护。我们主张在可能的情况下使用分支胸腹主动脉移植物进行个体化分支再植入,并且即使在MEP信号没有显著降低的情况下,我们也选择性地重新连接1对或多对下胸段肋间动脉和/或高位腰动脉。远端吻合通常在主动脉分叉上方构建,偶尔使用分叉移植物分别与每条髂动脉进行吻合。
在经验丰富的大容量中心,通过标准化的术前选择以及基于多学科团队的术中及术后管理,这些患者可以实现良好的早期结果和持久的TAAA修复。