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髂骨尤因肉瘤行部分骨盆切除术后的功能结果。

Functional results after partial pelvic resection in Ewing's sarcoma of the ilium.

作者信息

Porsch M, Kornhuber B, Hovy L

机构信息

Department of Orthopaedics, University of Frankfurt, Germany.

出版信息

Arch Orthop Trauma Surg. 1999;119(3-4):199-204. doi: 10.1007/s004020050390.

Abstract

Ewing's sarcoma of the pelvis has an unfavourable prognosis. The clinical and functional results of 7 patients who had a Ewing's sarcoma of the pelvis stage IIB were reviewed. All patients received multiple-agent chemotherapy pre- and postoperatively (modified T6 and T2 protocol according to Rosen) and underwent local resection of the pelvic tumour. According to Enneking, five patients had a type IA resection, one patient type I and another type IIA. One patient received a course of radiation therapy postoperatively (50 Gy). Six of seven patients showed a good regression of the tumour after preoperative chemotherapy. One patient who had a giant-cell Ewing's sarcoma died of local recurrence and lung metastases 29 months postoperatively. The remaining six patients were monitored radiographically and clinically according to Enneking's functional evaluation score after a follow-up period of 136 months (range 40-199 months). All were free of disease and had neither local recurrence nor metastases. In five patients the functional results were rated as "good" or "excellent". The good results depend mainly on the reconstruction of the pelvic girdle and its mechanical stability.

摘要

骨盆尤因肉瘤的预后不佳。回顾了7例骨盆IIB期尤因肉瘤患者的临床和功能结果。所有患者在术前和术后均接受了多药化疗(根据罗森的改良T6和T2方案),并接受了骨盆肿瘤的局部切除。根据恩内金的标准,5例患者进行了IA型切除,1例患者进行了I型切除,另1例进行了IIA型切除。1例患者术后接受了一个疗程的放射治疗(50 Gy)。7例患者中有6例在术前化疗后肿瘤出现了良好的消退。1例患有巨细胞尤因肉瘤的患者术后29个月死于局部复发和肺转移。其余6例患者在随访136个月(范围40 - 199个月)后,根据恩内金的功能评估评分进行了影像学和临床监测。所有患者均无疾病,无局部复发和转移。5例患者的功能结果被评为“良好”或“优秀”。良好的结果主要取决于骨盆带的重建及其机械稳定性。

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