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骨盆同种异体移植的高并发症发生率。22例肉瘤切除术的经验。

High complication rates with pelvic allografts. Experience of 22 sarcoma resections.

作者信息

Ozaki T, Hillmann A, Bettin D, Wuisman P, Winkelmann W

机构信息

Department of Orthopedics, Westfälische Wilhelms-University, Münster, Germany.

出版信息

Acta Orthop Scand. 1996 Aug;67(4):333-8. doi: 10.3109/17453679609002326.

DOI:10.3109/17453679609002326
PMID:8792734
Abstract

We performed 22 reconstructions by allografts in patients with pelvic sarcoma: 14 Ewing's sarcomas, 7 chondrosarcomas, and 1 osteosarcoma. All patients with Ewing's sarcoma and osteosarcoma received chemotherapy. No patients with chondrosarcoma had adjuvant treatment. 12 reconstructions were iliosacral arthrodesis after resection of an ilium tumor, 1 was iliofemoral arthrodesis and 9 were pelvic reconstructions with total hip prosthesis after resection of an acetabulum tumor. In the surviving patients, the mean length of follow-up was 4 (2-6) years. 2 allografts fractured and 8 allografts developed an infection. The infection was commoner in patients who had chondrosarcomas, large tumors, and a long operation time. Neither chemotherapy nor radiotherapy increased the infection rate. All infected allografts had to be removed.

摘要

我们对骨盆肉瘤患者进行了22例同种异体移植重建手术:14例尤因肉瘤、7例软骨肉瘤和1例骨肉瘤。所有尤因肉瘤和骨肉瘤患者均接受了化疗。软骨肉瘤患者均未接受辅助治疗。12例重建手术是在切除髂骨肿瘤后进行的髂骶关节融合术,1例是髂股关节融合术,9例是在切除髋臼肿瘤后使用全髋关节假体进行骨盆重建。在存活患者中,平均随访时间为4(2 - 6)年。2例同种异体移植发生骨折,8例发生感染。软骨肉瘤患者、肿瘤较大的患者和手术时间较长的患者感染更为常见。化疗和放疗均未增加感染率。所有感染的同种异体移植均必须移除。

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