Geronooz I, Scheen A J, Lefèbvre P J
Département de Médecine, Université de Liège.
Rev Med Liege. 1999 May;54(5):434-9.
Pregnancy is associated with important changes in mother metabolism, especially in late gestation, among which a decreased glucose tolerance caused by insulin resistance. In some of these women, glucose intolerance is increased by a defect in B-cell function and diabetes mellitus occurs. These women who develop a gestational diabetes need a close follow-up because they are at high risk for further development of diabetes, especially type 2 diabetes.
怀孕与母亲新陈代谢的重要变化有关,尤其是在妊娠晚期,其中胰岛素抵抗会导致葡萄糖耐量降低。在这些女性中,一些人的葡萄糖不耐受因β细胞功能缺陷而加重,进而发生糖尿病。这些患妊娠期糖尿病的女性需要密切随访,因为她们进一步发展为糖尿病尤其是2型糖尿病的风险很高。