Roth W D, von Smitten K, Heikkilä P, Edgren J, Laasonen L
Department of Radiology, Helsinki University, Central Hospital, Finland.
Acta Radiol. 1999 Jul;40(4):390-3. doi: 10.3109/02841859909177752.
To compare pathologic findings from stereotactic core and excisional biopsies in patients with microcalcifications in the breast.
Stereotactic core needle biopsies of 101 lesions with mammographic evidence of microcalcifications were performed with long-throw (2.2 cm) automated core biopsy devices fitted with 2.1-mm needles. The core specimens were placed on microscope slides and radiographed. The pathologic features of core and excisional specimens were compared.
In 100 of the 101 breast lesions, a correct choice for an additional diagnostic procedure or definitive treatment could have been made upon histopathologic findings of the core needle biopsy.
Stereotactic core needle biopsy is a reliable alternative to surgical biopsy of breast lesions with microcalcifications provided that specimen radiography has been performed to ensure that appropriate tissue has been obtained. Excisional biopsy may be avoided if microcalcifications are visible in radiographs of core biopsy specimen with benign histology.
比较乳腺微钙化患者立体定向粗针活检和切除活检的病理结果。
使用配备2.1毫米针的长投（2.2厘米）自动粗针活检装置，对101例有乳腺X线摄影微钙化证据的病变进行立体定向粗针活检。将粗针标本置于显微镜载玻片上并进行射线照相。比较粗针和切除标本的病理特征。
在101例乳腺病变中的100例中，根据粗针活检的组织病理学结果，本可对进一步的诊断程序或确定性治疗做出正确选择。
立体定向粗针活检是乳腺微钙化病变手术活检的可靠替代方法，前提是已进行标本射线照相以确保获取了合适的组织。如果粗针活检标本的射线照片显示微钙化且组织学为良性，则可避免切除活检。
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