Battaglia C, Genazzani A D, Salvatori M, Giulini S, Artini P G, Genazzani A R, Volpe A
Department of Obstetrics and Gynecology, University of Modena, Italy.
Gynecol Endocrinol. 1999 Apr;13(2):123-9. doi: 10.3109/09513599909167544.
The aim of this study was to evaluate how, in patients with polycystic ovary syndrome, the number of small subcapsular follicles correlates with uterine and ovarian blood flow and with specific hormonal parameters. At an ultrasonographic evaluation, 30 patients with polycystic ovary syndrome showed 5-10 (group I; n = 14) or > 10 (group II; n = 16) small follicles. These patients underwent ultrasonographic (ovarian volume and stroma echodensity; number, diameter and distribution of follicles) and color Doppler (uterine and intraovarian vessels) analyses, and hormonal assay. In group II, significantly lower pulsatility index values than in group I were observed in the ovarian stromal arteries. The Ferriman-Gallwey score, plasma androstenedione level and luteinizing hormone/follicle stimulating hormone (LH/FSH) ratio results were significantly higher in group II than in group I. Androstenedione plasma levels correlated with the number of small follicles. Furthermore, the LH/FSH ratio correlated with both the number of small follicles and the stromal artery pulsatility index. The combined assessment of ovarian morphology by transvaginal ultrasound and color Doppler may provide insight into the pathological state of polycystic ovary syndrome.
本研究的目的是评估多囊卵巢综合征患者的小囊下卵泡数量与子宫和卵巢血流以及特定激素参数之间的相关性。在超声检查中，30例多囊卵巢综合征患者显示有5 - 10个（第一组；n = 14）或> 10个（第二组；n = 16）小卵泡。这些患者接受了超声检查（卵巢体积和间质回声密度；卵泡数量、直径和分布）、彩色多普勒检查（子宫和卵巢内血管）以及激素测定。在第二组中，观察到卵巢间质动脉的搏动指数值显著低于第一组。第二组的费里曼 - 加韦评分、血浆雄烯二酮水平和促黄体生成素/促卵泡生成素（LH/FSH）比值结果显著高于第一组。血浆雄烯二酮水平与小卵泡数量相关。此外，LH/FSH比值与小卵泡数量和间质动脉搏动指数均相关。经阴道超声和彩色多普勒对卵巢形态的联合评估可能有助于深入了解多囊卵巢综合征的病理状态。
