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[启动大鼠胃壁舒张的内侧前庭核神经元]

[The neurons of the medial vestibular nucleus initiating the relaxation of the rat's stomach wall].

作者信息

Panteleev S S, Aleksandrov V G, Bagaev V A, Busygina I I, Liubashina O A

出版信息

Aviakosm Ekolog Med. 1999;33(2):15-9.

Abstract

In acute rat experiments the technique of retrograde axonal transport of horseradish peroxidase in the medial vestibular nucleus allowed to identify a group of neurones sending axons to the "stomach" region of a single tract nucleus. These neurones and, accordingly, the descending vestibular/solitary links can be viewed as the morphologic basis for vestibular influences on the gastric motor activity. As was shown, local irritation of the neurones initiates relaxation of the stomach wall. Activation of the anterior limbic cortex modulates the vestibular/autonomous responses of the intragastric pressure reduction. Irritation of the infralimbic cortex of the rat's brain may have a preventive effect on the stomach wall relaxation stimulated by the vestibular neurones projecting on the "stomach" region of single tract nucleus.

摘要

在急性大鼠实验中,利用辣根过氧化物酶在前庭内侧核中的逆行轴突运输技术,得以识别出一组向单一束状核的“胃”区发送轴突的神经元。这些神经元以及相应的前庭/孤束下行联系可被视为前庭对胃运动活动产生影响的形态学基础。研究表明,对这些神经元的局部刺激会引发胃壁松弛。前边缘皮层的激活会调节胃内压降低的前庭/自主反应。刺激大鼠脑的边缘下皮层可能对由投射到单一束状核“胃”区的前庭神经元所刺激的胃壁松弛具有预防作用。

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