Nevzgodina L V, Akatov Iu A, Arkhangel'skiĭ V V
Aviakosm Ekolog Med. 1999;33(2):42-4.
The authors analyzed the data about seeds of higher plants obtained in space experiments from several days to a year and a half in duration, and ground-based simulation studies on beams of accelerated heavy ions by the universal biological criterion of the chromosome aberrations. The criterion was also used to compare these data with those about lymphocytes in human peripheric blood in vitro. The number of aberrant cells, including cells with multiple aberrations, grew with mission duration, absorbed dose, and fluence of heavy charged particles as well as the topography of particles traverse of cells. Methodical dimensions of the test-object as a detector to evaluate the biological effects of and risk from space radiation in long-term space missions are considered.
作者依据染色体畸变这一通用生物学标准，分析了在为期数天至一年半的太空实验中获取的高等植物种子数据，以及基于地面的重离子加速束模拟研究数据。该标准还被用于将这些数据与人体外周血淋巴细胞的体外实验数据进行比较。异常细胞的数量，包括具有多个异常的细胞，随着飞行任务持续时间、吸收剂量、重带电粒子注量以及粒子穿过细胞的轨迹形态而增加。文中还探讨了将测试对象作为探测器来评估长期太空任务中空间辐射的生物学效应和风险的方法学维度。
