Podolec P, Pfitzner R, Wierzbicki K, Kostkiewicz M, Pieniazek P, Olszowska M, Przewlocki T, Sokolowski A, Tracz W, Dziatkowiak A
Department of Cardiovascular Diseases, Collegium Medicum, Jagiellonian University, Cracow, Poland.
J Heart Valve Dis. 1999 May;8(3):270-6.
The study aim was to evaluate the quality of life in patients after homograft or prosthetic aortic valve implantation. Evaluation was based on clinical and echocardiographic examinations, and on analysis of data from patient questionnaires.
Patients undergoing either homograft (HV, n = 220) or prosthetic (PV, n = 220) aortic valve replacement were investigated. The patients groups were similar in age, sex, follow up period, risk factors and type of heart defect, and did not demonstrate any dysfunction of the replacement valve.
During both pre- and postoperative periods, no significant inter-group differences were identified with regard to the occurrence of retrosternal pain, dyspnea, palpitation, fear reaction and circulatory efficiency based on NYHA classification, and self-evaluation of physical activity assessed by patient questionnaires. The majority of patients in both groups noticed on increase in their quality of life and physical activity. The reduced sexual activity (50%) and fear reaction (30%) in both groups did not correlate with their improved sense of well-being. Up to 14.6% of PV patients did not accept the implanted valve, and 65 (29.5%) would have preferred an HV, despite the need for reoperation. Following surgery, 21% of HV patients resumed work, compared with only 7.7% of PV patients. The frequency of claims for disability pension after surgery did not correlate with the considerate clinical and subjective improvement.
In patients receiving either homograft or prosthetic valves, the subjective evaluation of life quality is comparable with the clinical evaluation, though the homograft valve was better accepted than its prosthetic counterpart.
本研究旨在评估同种异体移植物或人工主动脉瓣植入术后患者的生活质量。评估基于临床和超声心动图检查,以及患者问卷数据分析。
对接受同种异体移植物(HV组,n = 220)或人工瓣膜(PV组,n = 220)主动脉瓣置换的患者进行调查。两组患者在年龄、性别、随访期、危险因素和心脏缺陷类型方面相似,且置换瓣膜均未出现功能障碍。
在术前和术后期间,基于纽约心脏病协会(NYHA)分级,两组在胸骨后疼痛、呼吸困难、心悸、恐惧反应和循环效率的发生情况,以及通过患者问卷评估的身体活动自我评估方面,均未发现显著的组间差异。两组中的大多数患者都注意到生活质量和身体活动有所提高。两组中性生活减少(50%)和恐惧反应(30%)与幸福感改善无关。高达14.6%的PV组患者不接受植入的瓣膜,65例(29.5%)患者更倾向于使用HV瓣膜,尽管需要再次手术。术后,21%的HV组患者恢复工作,而PV组患者仅为7.7%。术后申请残疾抚恤金的频率与可观的临床和主观改善无关。
在接受同种异体移植物或人工瓣膜的患者中,生活质量的主观评估与临床评估相当,尽管同种异体移植物瓣膜比人工瓣膜更易被接受。