Potemkowski A, Honczarenko K, Fabian A
Kliniki i Katedry Neurologii Pomorskiej, Akademii Medycznej w Szczecinie.
Neurol Neurochir Pol. 1999 Jan-Feb;33(1):71-8.
49 patients diagnosed as amyotrophic lateral sclerosis (ALS), hospitalized between 1986-1995, inhabitants of Szczecin-City were included in this study. ALS was diagnosed according to WFN criteria. The control group consisted of 60 people. Men:women ratio was 1.57:1. The mean age at ALS onset was 53.2 years. The disease was most often present between 51 and 60 years. Only one ALS patient was observed in the group of patients aged 21-30 and in the group of individuals older than 70 years. ALS incidence was 0.9 per 100,000 inhabitants and its prevalence in 1995 was 2.7 per 100,000 inhabitants. The mean duration was 30.8 months and was slightly higher in women. The shortest duration was observed in the bulbar form of ALS--21 months. Patients with ALS had been exposed to head trauma and contact with animals more often than the average population. There is no difference between Szczecin and previously analysed Polish cities in the considered epidemiological parameters. No discrepancies of clinical picture and course of the disease were found in comparison with other reported by other authors.
本研究纳入了1986年至1995年间在什切青市住院的49例被诊断为肌萎缩侧索硬化症（ALS）的患者。ALS根据世界神经病学联合会（WFN）标准进行诊断。对照组由60人组成。男女比例为1.57:1。ALS发病的平均年龄为53.2岁。该疾病最常出现在51至60岁之间。在21至30岁的患者组和70岁以上的个体组中仅观察到1例ALS患者。ALS发病率为每10万居民0.9例，1995年其患病率为每10万居民2.7例。平均病程为30.8个月，女性略高。延髓型ALS的病程最短——21个月。与普通人群相比，ALS患者头部外伤和接触动物的情况更为常见。在考虑的流行病学参数方面，什切青与之前分析过的波兰城市之间没有差异。与其他作者报告的情况相比，未发现疾病临床表现和病程存在差异。
