巴西南部阿雷格里港市肌萎缩侧索硬化症的患病率。
Prevalence of amyotrophic lateral sclerosis in the city of Porto Alegre, in Southern Brazil.
作者信息
Linden-Junior Eduardo, Becker Jefferson, Schestatsky Pedro, Rotta Francisco Tellechea, Marrone Carlo Domenico, Gomes Irenio
机构信息
Porto AlegreRS, Brazil.
Departamento de Neurologia, Pontifícia Universidade Católica do Rio Grande do Sul, Brazil, Porto AlegreRS.
出版信息
Arq Neuropsiquiatr. 2013 Dec;71(12):959-62. doi: 10.1590/0004-282X20130177.
OBJECTIVE
To determine the prevalence of amyotrophic lateral sclerosis (ALS) in the city of Porto Alegre, Brazil.
METHOD
We conducted an extensive investigation in clinics and hospitals that provide specialized assistance to these patients, contacted neurologists and the regional association of people with ALS.
RESULTS
On July 31, 2010, 70 patients were alive and diagnosed with amyotrophic lateral sclerosis. Considering the population living in the city in the same period (1,409,351), the estimated prevalence was 5.0 cases per 100,000 people (95% CI, 3.9-6.2), being higher for men (5.2/100,000 95% CI, 3.6-7.2) than for women (4.8/100,000 95% CI, 3.4-6.5). The prevalence increased with age peaking in the age group 70-79 years in both genders.
CONCLUSION
The prevalence of ALS in the city of Porto Alegre is similar to that reported in other parts of the world.
目的
确定巴西阿雷格里港肌萎缩侧索硬化症（ALS）的患病率。
方法
我们在为这些患者提供专科援助的诊所和医院进行了广泛调查，联系了神经科医生和ALS患者区域协会。
结果
2010年7月31日，70例患者存活且被诊断为肌萎缩侧索硬化症。考虑到同期该市的人口（1,409,351人），估计患病率为每10万人中有5.0例（95%可信区间，3.9 - 6.2），男性患病率（5.2/10万，95%可信区间，3.6 - 7.2）高于女性（4.8/10万，95%可信区间，3.4 - 6.5）。患病率随年龄增长而上升，在70 - 79岁年龄组中男女患病率均达到峰值。
结论
阿雷格里港肌萎缩侧索硬化症的患病率与世界其他地区报告的患病率相似。
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