Kaspera W, Majchrzak H, Banc K, Lelek P
Oddziału Neurochirurgii Szpitala Górniczego w Sosnowcu.
Neurol Neurochir Pol. 1999 Jan-Feb;33(1):97-117.
Seventeen cases (7 males and 10 females) of intracranial epidermoid tumours and one case (a male) of intracranial dermoid tumours were described. The patients with epidermoids represented 1.7% and the patients with dermoids represented 0.1% of all patients operated from January 1989 to July 1998 because of intracranial tumours. The average age of the patients with epidermoid tumours was 44.5 and ranged from 17 to 69 years whereas in patient with dermoid it was 19 years. Twelve epidermoid tumours (70.6%) and one dermoid tumour (100%) were located at the basal cisterns of the brain, i.e. 4 epidermoid tumours were located at the cerebello-pontine angle, 4--in the suprasellar region, 3 (2 epidermoid and 1 dermoid tumours)--in the parasellar region, and 2 in the retrosellar region. Four epidermoid tumours (23.5%) were found intraventricularly while only one (5.9%) located in the cerebral hemisphere. Mainly symptoms of cranial nerves (II, V, VII, VIII) dysfunction were observed among the patients. The average duration of the symptomatic period was 3 years. All operations were performed in a single stage using microneurosurgical techniques. Radical removal was possible in nine cases (50%) while in other nine cases the removal was subtotal. Two patients (11.1%) died in the postoperative period. Mean follow-up for the patients was 3.3 years. Among the patient three (16.7%) had a recurrence of the tumor and were operated on again. In 14 patients (72.2%) the results were very good and good. There was no difference of statistical significance of the results between patients with total and subtotal removal of tumours.
本文描述了17例颅内表皮样瘤(7例男性,10例女性)和1例颅内皮样瘤(1例男性)。在1989年1月至1998年7月因颅内肿瘤接受手术的所有患者中,表皮样瘤患者占1.7%,皮样瘤患者占0.1%。表皮样瘤患者的平均年龄为44.5岁,年龄范围在17至69岁之间,而皮样瘤患者的平均年龄为19岁。12例表皮样瘤(70.6%)和1例皮样瘤(100%)位于脑基底池,即4例表皮样瘤位于桥小脑角,4例位于鞍上区,3例(2例表皮样瘤和1例皮样瘤)位于鞍旁区,2例位于鞍后区。4例表皮样瘤(23.5%)位于脑室内,而仅1例(5.9%)位于脑半球。患者主要表现为颅神经(II、V、VII、VIII)功能障碍症状。症状期的平均持续时间为3年。所有手术均采用显微神经外科技术一次性完成。9例(50%)实现了根治性切除,其他9例为次全切除。2例患者(11.1%)在术后死亡。患者的平均随访时间为3.3年。3例患者(16.7%)肿瘤复发并再次接受手术。14例患者(72.2%)的治疗效果为非常好和良好。肿瘤全切和次全切患者的治疗效果在统计学上无显著差异。