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[颅内表皮样囊肿和皮样囊肿]

[Intracranial epidermoid and dermoid cysts].

作者信息

Gelabert-González M

机构信息

Servicio de Neurocirugía, Hospital General de Galicia, Universidad de Santiago de Compostela, España.

出版信息

Rev Neurol. 1998 Nov;27(159):777-82.

PMID:9859149
Abstract

INTRODUCTION

Dermoid and epidermoid cysts are dysembryogenic tumors representing 1% of all intracranial tumors. They are characterized by slow growth, localization to the middle in relation to the basal cisterns and their benign course.

OBJECTIVES

To analyze the clinical and radiological characteristics, and the results of surgical treatment of intracranial dermoid and epidermoid cysts.

PATIENTS AND METHODS

We reviewed 18 cases of epidermoid and 3 dermoid intracranial cysts which had been diagnosed and treated during a period of 18 years. All patients were diagnosed by computerized tomography (CT) and the last 15 cases by magnetic resonance (MR).

RESULTS

The commonest site was the temporal lobe with 7 cases, followed by the suprasellar region with 4 cases. All patients had peculiar imaging characteristics both on CT (hypodense and with no contrast silhouetted) and on MR (hypointensity in T1 and in T2). They were completely resected in 16 cases. There were 3 episodes of aseptic meningitis and 2 deaths.

CONCLUSIONS

Dermoid and epidermoid cysts are characterized by long term clinical symptoms. The commonest site is supratentorial in the midline or in the temporosylvian region. The diagnostic investigation of choice is MR. Treatment is surgical, preferably complete resection. However, after sub-total resection there is a prolonged period of remission.

摘要

引言

皮样囊肿和表皮样囊肿是胚胎发育异常性肿瘤,占所有颅内肿瘤的1%。它们的特点是生长缓慢,位于基底池中部,病程呈良性。

目的

分析颅内皮样囊肿和表皮样囊肿的临床及影像学特征,以及手术治疗结果。

患者与方法

我们回顾了18年间诊断并治疗的18例表皮样囊肿和3例皮样囊肿患者。所有患者均通过计算机断层扫描(CT)诊断,最后15例通过磁共振成像(MR)诊断。

结果

最常见的部位是颞叶,共7例,其次是鞍上区,共4例。所有患者在CT上(低密度且无强化轮廓)和MR上(T1和T2加权像均呈低信号)均具有独特的影像学特征。16例患者实现了完全切除。发生了3次无菌性脑膜炎,2例死亡。

结论

皮样囊肿和表皮样囊肿具有长期的临床症状。最常见的部位是幕上中线或颞叶区域。首选的诊断检查是MR。治疗方法是手术,最好是完全切除。然而,次全切除后也有较长的缓解期。

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