Peixoto A J, Reilly R F, Crowley S T
Section of Nephrology, Yale University School of Medicine, New Haven, CT, USA.
Am J Kidney Dis. 1999 Jul;34(1):161-5. doi: 10.1016/s0272-6386(99)70124-1.
The differentiation between atheroembolic disease (AED) and allergic interstitial nephritis (AIN) may pose a clinical challenge. Gallium scans have been proposed to identify AIN with good discriminating ability. We report herein a case of atheroembolic disease presenting as acute renal failure with persistent delayed uptake of gallium-67 by nuclear imaging. The distinction between AED and AIN could be made only with a renal biopsy, which confirmed the correct diagnosis. This case report and the presented review of the literature suggest that gallium scans are nonspecific and should not supplant renal biopsy for definitive histological diagnosis.
动脉粥样硬化栓塞性疾病（AED）与过敏性间质性肾炎（AIN）的鉴别可能会带来临床挑战。有人提出用镓扫描来鉴别AIN，其具有良好的鉴别能力。我们在此报告一例以急性肾衰竭为表现的动脉粥样硬化栓塞性疾病，核成像显示镓 - 67持续摄取延迟。只有通过肾活检才能区分AED和AIN，肾活检证实了正确的诊断。本病例报告及所呈现的文献综述表明，镓扫描是非特异性的，不应取代肾活检以进行明确的组织学诊断。
