Suppr超能文献

破裂性主髂动脉瘤的血管腔内移植物修复术。

Endovascular graft repair of ruptured aortoiliac aneurysms.

作者信息

Ohki T, Veith F J, Sanchez L A, Cynamon J, Lipsitz E C, Wain R A, Morgan J A, Zhen L, Suggs W D, Lyon R T

机构信息

Department of Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, New York, NY 10467, USA.

出版信息

J Am Coll Surg. 1999 Jul;189(1):102-12; discussion 112-3. doi: 10.1016/s1072-7515(99)00051-4.

Abstract

BACKGROUND

The feasibility of endovascular graft (EVG) repair of ruptured aortoiliac aneurysms (AIAs) has yet to be demonstrated. There are inherent limitations in EVG repair, including the need for preoperative measurements of the aneurysmal and adjacent arterial anatomy to determine the appropriate size and type of graft and the inherent delay to obtain proximal occlusion. We developed an EVG system with broad versatility that largely eliminates these problems.

STUDY DESIGN

Between 1993 and 1998, within an experience of 134 endovascular AIA repairs, 12 ruptured AIAs were treated using EVGs that facilitated intraoperative customization and eliminated the need for preoperative measurements. The EVGs consisted of either a Palmaz stent and a PTFE graft deployed by a compliant balloon (n = 9) or a self-expanding covered stent graft (n = 3). Both grafts were cut to the appropriate length intraoperatively. The mean age of the patients was 72 years (range 40 to 86 years). The mean size of the aneurysms was 7.6 cm (range 3 to 16 cm). Preoperative symptoms were present in all patients and included abdominal or back pain (n = 9), syncope (n = 4), and external bleeding (n = 2). All patients were high surgical risks because of comorbid disease (n = 10) or previous abdominal operations (n = 6), and nine experienced hypotension.

RESULTS

All EVGs were inserted successfully and excluded the aneurysms from the circulation. The mean operating time was 263 minutes, the mean blood loss was 715 mL, and the mean length of hospital stay was 6.5 days. There were two deaths (16%), one from the preexisting acute myocardial infarction and one from multiple organ failure. There were three minor complications (25%). Two patients required evacuation of an intraabdominal hematoma from the initial rupture. All but one of the grafts was functioning at a mean followup of 18 months.

CONCLUSIONS

This study demonstrates the feasibility of EVG repair for ruptured AIAs using a graft that can be customized intraoperatively for each patient. Such repairs currently are valuable in patients with ruptured AIAs and serious comorbidities and may be applicable in other circumstances as well.

摘要

背景

血管内移植物(EVG)修复破裂性主髂动脉瘤(AIA)的可行性尚未得到证实。EVG修复存在固有局限性,包括术前需要测量动脉瘤及相邻动脉解剖结构以确定合适的移植物尺寸和类型,以及获得近端闭塞存在固有延迟。我们开发了一种具有广泛通用性的EVG系统,很大程度上消除了这些问题。

研究设计

1993年至1998年期间,在134例血管内AIA修复经验中,12例破裂性AIA使用了便于术中定制且无需术前测量的EVG进行治疗。这些EVG由Palmaz支架和通过顺应性球囊展开的PTFE移植物组成(n = 9)或自膨式覆膜支架移植物(n = 3)。两种移植物均在术中裁剪至合适长度。患者的平均年龄为72岁(范围40至86岁)。动脉瘤的平均大小为7.6 cm(范围3至16 cm)。所有患者术前均有症状,包括腹痛或背痛(n = 9)、晕厥(n = 4)和外出血(n = 2)。由于合并症(n = 10)或既往腹部手术(n = 6),所有患者均为高手术风险,9例出现低血压。

结果

所有EVG均成功植入,使动脉瘤从循环中排除。平均手术时间为263分钟,平均失血量为715 mL,平均住院时间为6.5天。有2例死亡(16%),1例死于既往急性心肌梗死,1例死于多器官功能衰竭。有3例轻微并发症(25%)。2例患者需要清除最初破裂导致的腹腔内血肿。除1例移植物外,所有移植物在平均18个月的随访中均功能良好。

结论

本研究证明了使用可在术中为每位患者定制的移植物进行EVG修复破裂性AIA的可行性。此类修复目前对于破裂性AIA和严重合并症患者具有重要价值,也可能适用于其他情况。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验