Baratawidjaja I R, Baratawidjaja P P, Darwis A, Soo-Hwee L, Fook-Tim C, Bee-Wah L, Baratawidjaja K G
Department of Internal Medicine, University of Indonesia, Jakarta, Indonesia.
Asian Pac J Allergy Immunol. 1999 Mar;17(1):9-12.
Sensitization towards a panel of eight regional inhalant allergens was evaluated among 107 patients with allergic rhinitis and/or asthma. A total of 32 children (age 5-13 years, mean 9 years; 18 male, 14 female), 75 adolescents and adults (aged 14-66 years, mean 32 years; 21 male, 54 female) and 20 normal control volunteers (aged 16-46, mean 30 years; 4 male, 16 female) were evaluated via skin prick test. A weal response of 3 x 3 mm or greater was taken to be positive. The sensitization rates among individuals to these allergens were: house dust mites, Dermatophagoides pteronyssinus (77.57%), Blomia tropicalis (71.96%), Austroglycyphagus malaysiensis (33.64%), pollen, palm oil Elaeis guineensis (22.43%), Acacia auriculiformis (12.15%), fern spore, resam Dicranopteris spp (11.21%), fungal spores: Curvularia fallax (8.41%) and Exserohilum rostratum (13.08%). There were significantly higher frequencies of sensitization to these allergens among allergic individuals compared to normal controls, and among atopic individuals with two allergy manifestations (rhinitis and asthma) compared to those with only one. No difference was noted between children and adults in the allergic group. In conclusion, the allergic patients were highly sensitized to dust mites and sensitization to regional pollen and spores was also documented. They should be considered as relevant and be included in skin test batteries in Indonesia.
在107例过敏性鼻炎和/或哮喘患者中评估了对一组8种区域性吸入性变应原的致敏情况。通过皮肤点刺试验对32名儿童（年龄5 - 13岁，平均9岁；18名男性，14名女性）、75名青少年和成年人（年龄14 - 66岁，平均32岁；21名男性，54名女性）以及20名正常对照志愿者（年龄16 - 46岁，平均30岁；4名男性，16名女性）进行了评估。风团反应3×3毫米或更大被视为阳性。个体对这些变应原的致敏率分别为：屋尘螨，粉尘螨（77.57%）、热带无爪螨（71.96%）、马来西亚嗜甜螨（33.64%）、花粉，油棕（22.43%）、耳叶相思（12.15%）、蕨类孢子，芒萁（11.21%）、真菌孢子：伪弯孢（8.41%）和喙突埃里格孢（13.08%）。与正常对照相比，过敏个体对这些变应原的致敏频率显著更高；与仅有一种过敏表现的个体相比，有两种过敏表现（鼻炎和哮喘）的特应性个体致敏频率更高。过敏组中儿童和成年人之间未观察到差异。总之，过敏患者对尘螨高度致敏，对区域性花粉和孢子的致敏情况也有记录。在印度尼西亚，应将它们视为相关变应原并纳入皮肤试验组合中。
