Avasthi A, Sharma A, Malhotra S, Gupta N, Kulhara P, Malhotra S
Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
J Affect Disord. 1999 Jul;54(1-2):67-73. doi: 10.1016/s0165-0327(98)00135-9.
A series of 33 (4.29%) cases of rapid cycling affective disorder (RCAD ICD-10-DCR) out of a pool of 770 consecutive cases of ICD-10 affective disorder (AD) was collected over a period of 5 years. All cases of RCAD belonged to bipolar affective disorder. RCAD when compared with non-rapid cycling bipolar affective disorder (BPAD) revealed a significantly longer mean duration of illness, greater number of total episodes, greater number of hospitalizations and stronger family loading of bipolar affective disorder. These findings implicate RCAD as a severe form of bipolar affective disorder.
在连续770例国际疾病分类第10版（ICD - 10）情感障碍（AD）患者中，历时5年收集到33例（4.29%）快速循环型情感障碍（RCAD，ICD - 10 - DCR）患者。所有RCAD病例均属于双相情感障碍。与非快速循环型双相情感障碍（BPAD）相比，RCAD的平均病程显著更长，总发作次数更多，住院次数更多，双相情感障碍的家族负荷更强。这些发现表明RCAD是双相情感障碍的一种严重形式。
