IM - 133的免疫调节作用
Immunomodulatory effect of IM-133.
作者信息
Mitra S K, Gupta M, Sarma D N
机构信息
R & D Centre, Himalaya Drug Company, Makali, Bangalore, India.
出版信息
Phytother Res. 1999 Jun;13(4):341-3. doi: 10.1002/(SICI)1099-1573(199906)13:4<341::AID-PTR410>3.0.CO;2-6.
The immunomodulatory effect of IM-133, a polyherbal formulation, has been investigated. Treatment with IM-133 enhanced the delayed type hypersensitivity (DTH) response in mice. IM-133 enhanced the in vitro response of splenocytes to mitogenic challenge. The in vivo treatment also stimulated the ex vivo lymphocyte proliferation, while the humoral response to sheep RBCs (SRBCs) was unaffected. The preferential stimulation of the components of cell mediated immunity (CMI) indicate that treatment with IM-133 affords non-specific immune stimulation.
已对复方草药制剂IM - 133的免疫调节作用进行了研究。用IM - 133处理可增强小鼠的迟发型超敏反应（DTH）。IM - 133增强了脾细胞对有丝分裂原刺激的体外反应。体内处理还刺激了离体淋巴细胞增殖，而对绵羊红细胞（SRBC）的体液反应未受影响。对细胞介导免疫（CMI）成分的优先刺激表明，用IM - 133处理可提供非特异性免疫刺激。
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