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气囊扩张术后食管排空的评估:定时钡剂食管造影的应用

Assessment of esophageal emptying post-pneumatic dilation: use of the timed barium esophagram.

作者信息

Vaezi M F, Baker M E, Richter J E

机构信息

Center for Swallowing and Esophageal Disorders, Department of Gastroenterology, Cleveland Clinic Foundation, Ohio 44195, USA.

出版信息

Am J Gastroenterol. 1999 Jul;94(7):1802-7. doi: 10.1111/j.1572-0241.1999.01209.x.

Abstract

OBJECTIVES

The reported success rate of pneumatic dilation in patients with achalasia varies from 50% to 93%. This wide variability may be due to using symptom relief post-dilation as the only assessment of success. There are no studies comparing subjective symptom improvements to objective improvement in esophageal emptying after pneumatic dilation.

METHODS

Patients with achalasia undergoing pneumatic dilation from 1995 to 1997 were evaluated. Pre- and post-dilation symptoms were recorded using a standardized scoring system. Barium column height was measured 1 min and 5 min after upright ingestion to assess esophageal emptying. Based on percentage of total symptom and barium height improvement post-dilation, patients were grouped according to one of nine outcomes; the association between subjective and objective parameters of improvement was tested.

RESULTS

A total of 37 patients underwent 53 pneumatic dilations. There was a significant association (p < 0.001) between improvement in patient symptoms and barium height. In 38 of 53 (72%) pneumatic dilations, the degree of symptom and barium height improvement was similar. Near complete symptom resolution was reported after 26 dilations. In eight of 26 (31%) patients however, there was < 50% improvement in barium height (group A). Compared with the 16 patients with 91-100% improvement in both symptoms and barium height (group B), forward stepwise regression identified age as the only difference between the two groups, with group A patients being significantly (p = 0.04) older.

CONCLUSIONS

Objective assessment of esophageal emptying pre- and post-dilation identifies an important subset of patients with poor esophageal emptying who report near complete symptom resolution. This group may benefit from any early repeat pneumatic dilation.

摘要

目的

贲门失弛缓症患者经气囊扩张术的报道成功率在50%至93%之间。这种较大的差异可能是由于仅将扩张后症状缓解作为成功的唯一评估标准。目前尚无研究比较主观症状改善与气囊扩张术后食管排空客观改善情况。

方法

对1995年至1997年接受气囊扩张术的贲门失弛缓症患者进行评估。使用标准化评分系统记录扩张前后的症状。在直立吞咽后1分钟和5分钟测量钡剂柱高度以评估食管排空情况。根据扩张后总症状和钡剂高度改善的百分比,将患者分为九种结果之一;测试主观和客观改善参数之间的关联。

结果

共有37例患者接受了53次气囊扩张术。患者症状改善与钡剂高度之间存在显著关联(p<0.001)。在53次(72%)气囊扩张术中,有38次症状和钡剂高度改善程度相似。26次扩张术后报告症状几乎完全缓解。然而,在这26例患者中的8例(31%),钡剂高度改善<50%(A组)。与16例症状和钡剂高度均改善91%-100%的患者(B组)相比,向前逐步回归分析确定年龄是两组之间的唯一差异,A组患者年龄显著更大(p=0.04)。

结论

扩张前后对食管排空进行客观评估可识别出一组食管排空不良但报告症状几乎完全缓解的重要患者亚组。该组患者可能从早期重复气囊扩张术中获益。

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