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贲门失弛缓症内镜及手术治疗后的影像学表现。

Imaging following endoscopic and surgical treatment of achalasia.

作者信息

Flicek Kristina T, Carucci Laura R, Turner Mary Ann

机构信息

Mayo Clinic, Rochester, USA.

Virginia Commonwealth University, Richmond, USA.

出版信息

Abdom Radiol (NY). 2025 May;50(5):1942-1952. doi: 10.1007/s00261-024-04663-4. Epub 2024 Nov 19.

Abstract

Achalasia is an esophageal motility disorder characterized by absent esophageal peristalsis associated with failure of relaxation of the lower esophageal sphincter (LES). Patients with achalasia may present with long-standing and slowly progressive dysphagia to solids and liquids, heartburn, regurgitation, refractory reflux symptoms and noncardiac chest pain. The esophagram and the timed barium swallow are useful imaging studies that may contribute to the diagnosis of achalasia and may be used to determine improvement after treatment. Esophagography is also ideally suited to evaluate potential post treatment complications. Treatment options for achalasia aim to disrupt the high-pressure LES to improve esophageal emptying, improve symptoms and prevent further dilatation of the esophagus. The most common treatment options currently include esophageal botulinum toxin (Botox) injections, pneumatic dilatation, Heller myotomy (often performed in conjunction with a fundoplication) and peroral endoscopic myotomy. Potential complications of these procedures may include intramural dissection, leak, scarring and fibrosis of the lower esophagus, strictures and problems related to gastroesophageal reflux and its associated complications. Radiologists must be aware of expected findings and potential complications following these procedures for timely and accurate diagnoses. The purpose of this paper is to describe treatment options for achalasia, illustrate expected imaging findings as well as imaging findings of potential early and long-term complications following treatment for achalasia.

摘要

贲门失弛缓症是一种食管动力障碍性疾病,其特征为食管蠕动缺失,并伴有食管下括约肌(LES)松弛功能障碍。贲门失弛缓症患者可能长期存在且逐渐进展的固体和液体吞咽困难、烧心、反流、难治性反流症状以及非心源性胸痛。食管造影和定时吞钡检查是有用的影像学检查,有助于贲门失弛缓症的诊断,并可用于确定治疗后的改善情况。食管造影也非常适合评估潜在的治疗后并发症。贲门失弛缓症的治疗方案旨在破坏高压的LES,以改善食管排空、缓解症状并防止食管进一步扩张。目前最常见的治疗方案包括食管肉毒杆菌毒素(肉毒素)注射、气囊扩张、Heller肌切开术(通常与胃底折叠术联合进行)以及经口内镜下肌切开术。这些手术的潜在并发症可能包括壁内剥离、渗漏、食管下段瘢痕形成和纤维化、狭窄以及与胃食管反流及其相关并发症有关的问题。放射科医生必须了解这些手术后预期的表现和潜在并发症,以便及时准确地进行诊断。本文的目的是描述贲门失弛缓症的治疗方案,说明预期的影像学表现以及贲门失弛缓症治疗后潜在的早期和长期并发症的影像学表现。

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