Ho A K, Iansek R, Bradshaw J L
Neuropsychology Research Unit, Psychology Department, Monash University, Clayton 3168, Victoria, Australia.
J Neurol Neurosurg Psychiatry. 1999 Aug;67(2):199-202. doi: 10.1136/jnnp.67.2.199.
This study examined the automatic regulation of speech volume over distance in hypophonic patients with Parkinson's disease and age and sex matched controls. There were two speech settings; conversation, and the recitation of sequential material (for example, counting). The perception of interlocuter speech volume by patients with Parkinson's disease and controls over varying distances was also examined, and found to be slightly discrepant. For speech production, it was found that controls significantly increased overall speech volume for conversation relative to that for sequential material. Patients with Parkinson's disease were unable to achieve this overall increase for conversation, and consistently spoke at a softer volume than controls at all distances (intercept reduction). However, patients were still able to increase volume for greater distances in a similar way to controls for conversation and sequential material, thus showing a normal pattern of volume regulation (slope similarity). It is suggested that speech volume regulation is intact in Parkinson's disease, but rather the gain is reduced. These findings are reminiscent of skeletal motor control studies in Parkinson's disease, in which the amplitude of movement is diminished but the relation with another factor is preserved (stride length increases as cadence-that is, stepping rate, increases).
本研究调查了帕金森病轻声患者以及年龄和性别匹配的对照组在不同距离下对语音音量的自动调节情况。有两种语音场景：对话和背诵连续的材料（例如数数）。研究还考察了帕金森病患者和对照组在不同距离下对交谈对象语音音量的感知，发现二者略有差异。对于语音产生，研究发现，与背诵连续材料相比，对照组在对话时显著提高了总体语音音量。帕金森病患者在对话时无法实现这种总体音量的增加，并且在所有距离下说话声音都始终比对照组轻柔（截距降低）。然而，患者在对话和背诵连续材料时，仍能像对照组一样，随着距离增加而提高音量，从而表现出正常的音量调节模式（斜率相似）。研究表明，帕金森病患者的语音音量调节功能是完整的，只是增益降低。这些发现让人联想到帕金森病的骨骼肌运动控制研究，其中运动幅度减小，但与另一个因素的关系得以保留（步幅随着节奏即步频增加而增加）。
