Faculty of Health Sciences, Centre for Rehabilitation & Special Needs, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Department of Special Education and Communication Disorders and Department of Biological Systems Engineering, Center for Brain, Biology and Behavior, University of Nebraska, Lincoln, NE, USA.
Int J Speech Lang Pathol. 2020 Apr;22(2):141-151. doi: 10.1080/17549507.2019.1622781. Epub 2019 Jun 18.
: To characterise labial articulatory pattern variability using the spatiotemporal index (STI) in speakers with idiopathic Parkinson's disease (PD) across different speaking rates and syllable-sentence conditions compared to age- and sex-matched healthy controls.: Ten speakers with mild-severe idiopathic PD and 10 controls produced "pa" and the Rainbow Passage at slow, typical and fast speech rates. Upper lip and lower lip kinematics were digitised during a motion capture system. Data were analysed using linear mixed modelling.: Regardless of the participant group, a high STI value was observed in the fast speech rate for the "pa" syllable condition, particularly for movements of the lower lip. As utterance rate increased, the control group showed the highest variability, followed by PD OFF and PD ON conditions. Syllable "pa" showed a greater STI value compared to both the first and second utterance of Rainbow Passage.: PD manifests sufficient residual capacity to achieve near-normal motor compensation to preserve the consistency of lower lip movements during speech production. The lack of a significant difference in lip STI values between ON-OFF medication states suggests that dopaminergic treatment does not influence stability of speech for individuals with mild-moderate stage PD.
: 使用时空指数(STI)来描述特发性帕金森病(PD)患者的唇动模式变异性,与年龄和性别匹配的健康对照者相比,在不同的语速和音节-句子条件下进行比较。: 10 名轻度至重度特发性 PD 患者和 10 名对照者以慢、中、快语速说出“pa”和彩虹通道。在运动捕捉系统中对上唇和下唇运动进行了数字化。使用线性混合模型对数据进行了分析。: 无论参与者组如何,在快速语速下,“pa”音节条件下的 STI 值较高,尤其是下唇运动。随着语速的增加,对照组显示出最大的变异性,其次是 PD OFF 和 PD ON 条件。与彩虹通道的第一和第二句话相比,音节“pa”显示出更高的 STI 值。: PD 表现出足够的剩余能力来实现接近正常的运动补偿,以保持言语产生过程中下唇运动的一致性。在 ON-OFF 药物状态下,唇部 STI 值没有显著差异,这表明多巴胺治疗不会影响轻度至中度 PD 患者的言语稳定性。