Vandevska-Radunovic V
Department of Anatomy and Cell Biology, University of Bergen, Norway.
Eur J Orthod. 1999 Jun;21(3):231-47. doi: 10.1093/ejo/21.3.231.
This article reviews the current knowledge of the biological aspects of dental tissue changes incident to orthodontic tooth movement. The inflammatory nature of these tissue changes was first recognized in the early 1970s, and since then a number of morphological and quantitative investigations have been published in support of this view. The studies dealing with vascular and cellular dental tissue changes, as well as those concerned with inflammatory mediators present at sites of orthodontic tooth movement are systematized and presented accordingly. Special emphasis is placed upon the role of the sensory nerve fibres and their neuropeptides in the control, and development of an inflammatory process, i.e. their role in tooth movement.
本文综述了正畸牙齿移动引起的牙齿组织变化的生物学方面的现有知识。这些组织变化的炎症性质在20世纪70年代初首次被认识到，从那时起，已经发表了许多形态学和定量研究来支持这一观点。本文对涉及牙齿血管和细胞组织变化的研究，以及与正畸牙齿移动部位存在的炎症介质有关的研究进行了系统整理并相应呈现。特别强调了感觉神经纤维及其神经肽在炎症过程的控制和发展中的作用，即它们在牙齿移动中的作用。
