Duff J M, Spinner R J, Lindor N M, Dodick D W, Atkinson J L
Department of Neurosurgery, Mayo Clinic, Rochester, MN 55905, USA.
Neurology. 1999 Jul 13;53(1):216-8. doi: 10.1212/wnl.53.1.216.
A patient was evaluated with familial trigeminal neuralgia (TN) and contralateral hemifacial spasm. The mother of the patient, 5 of 10 siblings, and 1 nephew also had TN confirmed by neurologists. The transmission of TN was suggestive of an autosomal dominant inheritance. This family provides additional evidence of a genetic basis for TN in selected cases and also provokes further speculation on a common unifying hypothesis of pathophysiology in cranial rhizopathies.
一名患有家族性三叉神经痛（TN）和对侧半面痉挛的患者接受了评估。该患者的母亲、10个兄弟姐妹中的5个以及1个侄子也被神经科医生确诊患有TN。TN的遗传方式提示为常染色体显性遗传。这个家族为某些病例中TN的遗传基础提供了额外证据，也引发了对颅神经根病病理生理学共同统一假说的进一步猜测。
